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The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release.
Düsterhöft S, Kahveci-Türköz S, Wozniak J, Seifert A, Kasparek P, Ohm H, Liu S, Kopkanova J, Lokau J, Garbers C, Preisinger C, Sedlacek R, Freeman M, Ludwig A. Düsterhöft S, et al. Among authors: preisinger c. Cell Mol Life Sci. 2021 Jun;78(11):5015-5040. doi: 10.1007/s00018-021-03845-3. Epub 2021 May 5. Cell Mol Life Sci. 2021. PMID: 33950315 Free PMC article.
Desmoglein 2, but not desmocollin 2, protects intestinal epithelia from injury.
Gross A, Pack LAP, Schacht GM, Kant S, Ungewiss H, Meir M, Schlegel N, Preisinger C, Boor P, Guldiken N, Krusche CA, Sellge G, Trautwein C, Waschke J, Heuser A, Leube RE, Strnad P. Gross A, et al. Among authors: preisinger c. Mucosal Immunol. 2018 Nov;11(6):1630-1639. doi: 10.1038/s41385-018-0062-z. Epub 2018 Aug 16. Mucosal Immunol. 2018. PMID: 30115995 Free article.
The nucleoporin Nup50 activates the Ran guanine nucleotide exchange factor RCC1 to promote NPC assembly at the end of mitosis.
Holzer G, De Magistris P, Gramminger C, Sachdev R, Magalska A, Schooley A, Scheufen A, Lennartz B, Tatarek-Nossol M, Lue H, Linder MI, Kutay U, Preisinger C, Moreno-Andres D, Antonin W. Holzer G, et al. Among authors: preisinger c. EMBO J. 2021 Dec 1;40(23):e108788. doi: 10.15252/embj.2021108788. Epub 2021 Nov 2. EMBO J. 2021. PMID: 34725842 Free PMC article.
RIPK1 Suppresses a TRAF2-Dependent Pathway to Liver Cancer.
Schneider AT, Gautheron J, Feoktistova M, Roderburg C, Loosen SH, Roy S, Benz F, Schemmer P, Büchler MW, Nachbur U, Neumann UP, Tolba R, Luedde M, Zucman-Rossi J, Panayotova-Dimitrova D, Leverkus M, Preisinger C, Tacke F, Trautwein C, Longerich T, Vucur M, Luedde T. Schneider AT, et al. Among authors: preisinger c. Cancer Cell. 2017 Jan 9;31(1):94-109. doi: 10.1016/j.ccell.2016.11.009. Epub 2016 Dec 22. Cancer Cell. 2017. PMID: 28017612 Free article.
Dual proteotoxic stress accelerates liver injury via activation of p62-Nrf2.
Kuscuoglu D, Bewersdorf L, Wenzel K, Gross A, Kobazi Ensari G, Luo Y, Kilic K, Hittatiya K, Golob-Schwarzl N, Leube RE, Preisinger C, George J, Metwally M, Eslam M, Lampertico P, Petta S, Mangia A, Berg T, Boonstra A, Brouwer WP, Abate ML, Loglio A, Sutton A, Nahon P, Schaefer B, Zoller H, Aigner E, Trautwein C, Haybaeck J, Strnad P. Kuscuoglu D, et al. Among authors: preisinger c. J Pathol. 2021 May;254(1):80-91. doi: 10.1002/path.5643. Epub 2021 Mar 18. J Pathol. 2021. PMID: 33586163 Free article.
Combined Activities of JNK1 and JNK2 in Hepatocytes Protect Against Toxic Liver Injury.
Cubero FJ, Zoubek ME, Hu W, Peng J, Zhao G, Nevzorova YA, Al Masaoudi M, Bechmann LP, Boekschoten MV, Muller M, Preisinger C, Gassler N, Canbay AE, Luedde T, Davis RJ, Liedtke C, Trautwein C. Cubero FJ, et al. Among authors: preisinger c. Gastroenterology. 2016 Apr;150(4):968-81. doi: 10.1053/j.gastro.2015.12.019. Epub 2015 Dec 19. Gastroenterology. 2016. PMID: 26708719 Free PMC article.
JNK signaling prevents biliary cyst formation through a CASPASE-8-dependent function of RIPK1 during aging.
Müller K, Honcharova-Biletska H, Koppe C, Egger M, Chan LK, Schneider AT, Küsgens L, Böhm F, Boege Y, Healy ME, Schmitt J, Comtesse S, Castoldi M, Preisinger C, Szydlowska M, Focaccia E, Gaisa NT, Loosen SH, Jörs S, Tacke F, Roderburg C, Keitel V, Bode JG, Boor P, Davis RJ, Longerich T, Geisler F, Heikenwalder M, Weber A, Vucur M, Luedde T. Müller K, et al. Among authors: preisinger c. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2007194118. doi: 10.1073/pnas.2007194118. Proc Natl Acad Sci U S A. 2021. PMID: 33798093 Free PMC article.
55 results