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Chronic wasting disease.
Prcina M, Bardon J, Kontseková E. Prcina M, et al. Acta Virol. 2008;52(4):209-18. Acta Virol. 2008. PMID: 19143476 Review.
Tauons and prions: infamous cousins?
Novak P, Prcina M, Kontsekova E. Novak P, et al. Among authors: prcina m. J Alzheimers Dis. 2011;26(3):413-30. doi: 10.3233/JAD-2011-110194. J Alzheimers Dis. 2011. PMID: 21694453 Review.
Safety and immunogenicity of the tau vaccine AADvac1 in patients with Alzheimer's disease: a randomised, double-blind, placebo-controlled, phase 1 trial.
Novak P, Schmidt R, Kontsekova E, Zilka N, Kovacech B, Skrabana R, Vince-Kazmerova Z, Katina S, Fialova L, Prcina M, Parrak V, Dal-Bianco P, Brunner M, Staffen W, Rainer M, Ondrus M, Ropele S, Smisek M, Sivak R, Winblad B, Novak M. Novak P, et al. Among authors: prcina m. Lancet Neurol. 2017 Feb;16(2):123-134. doi: 10.1016/S1474-4422(16)30331-3. Epub 2016 Dec 10. Lancet Neurol. 2017. PMID: 27955995 Clinical Trial.
FUNDAMANT: an interventional 72-week phase 1 follow-up study of AADvac1, an active immunotherapy against tau protein pathology in Alzheimer's disease.
Novak P, Schmidt R, Kontsekova E, Kovacech B, Smolek T, Katina S, Fialova L, Prcina M, Parrak V, Dal-Bianco P, Brunner M, Staffen W, Rainer M, Ondrus M, Ropele S, Smisek M, Sivak R, Zilka N, Winblad B, Novak M. Novak P, et al. Among authors: prcina m. Alzheimers Res Ther. 2018 Oct 24;10(1):108. doi: 10.1186/s13195-018-0436-1. Alzheimers Res Ther. 2018. PMID: 30355322 Free PMC article. Clinical Trial.
Therapeutic antibody targeting microtubule-binding domain prevents neuronal internalization of extracellular tau via masking neuron surface proteoglycans.
Weisová P, Cehlár O, Škrabana R, Žilková M, Filipčík P, Kováčech B, Prčina M, Wojčiaková Ľ, Fialová Ľ, Smolek T, Kontseková E, Žilka N, Novák M. Weisová P, et al. Among authors: prcina m. Acta Neuropathol Commun. 2019 Aug 7;7(1):129. doi: 10.1186/s40478-019-0770-y. Acta Neuropathol Commun. 2019. PMID: 31391090 Free PMC article.
Humanized tau antibodies promote tau uptake by human microglia without any increase of inflammation.
Zilkova M, Nolle A, Kovacech B, Kontsekova E, Weisova P, Filipcik P, Skrabana R, Prcina M, Hromadka T, Cehlar O, Rolkova GP, Maderova D, Novak M, Zilka N, Hoozemans JJM. Zilkova M, et al. Among authors: prcina m. Acta Neuropathol Commun. 2020 May 29;8(1):74. doi: 10.1186/s40478-020-00948-z. Acta Neuropathol Commun. 2020. PMID: 32471486 Free PMC article.
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