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Donepezil Derivatives Targeting Amyloid-β Cascade in Alzheimer's Disease.
Mezeiova E, Chalupova K, Nepovimova E, Gorecki L, Prchal L, Malinak D, Kuca K, Soukup O, Korabecny J. Mezeiova E, et al. Among authors: prchal l. Curr Alzheimer Res. 2019;16(9):772-800. doi: 10.2174/1567205016666190228122956. Curr Alzheimer Res. 2019. PMID: 30819078 Review.
A novel class of small molecule inhibitors with radioprotective properties.
Marek J, Tichy A, Havelek R, Seifrtova M, Filipova A, Andrejsova L, Kucera T, Prchal L, Muckova L, Rezacova M, Sinkorova Z, Pejchal J. Marek J, et al. Among authors: prchal l. Eur J Med Chem. 2020 Feb 1;187:111606. doi: 10.1016/j.ejmech.2019.111606. Epub 2020 Jan 1. Eur J Med Chem. 2020. PMID: 31901334
Substituted Piperazines as Novel Potential Radioprotective Agents.
Filipova A, Marek J, Havelek R, Pejchal J, Jelicova M, Cizkova J, Majorosova M, Muckova L, Kucera T, Prchal L, Psotka M, Zivna N, Koutova D, Sinkorova Z, Rezacova M, Tichy A. Filipova A, et al. Among authors: prchal l. Molecules. 2020 Jan 25;25(3):532. doi: 10.3390/molecules25030532. Molecules. 2020. PMID: 31991816 Free PMC article.
Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer's Disease Treatment.
Schmidt M, Benek O, Vinklarova L, Hrabinova M, Zemanova L, Chribek M, Kralova V, Hroch L, Dolezal R, Lycka A, Prchal L, Jun D, Aitken L, Gunn-Moore F, Kuca K, Musilek K. Schmidt M, et al. Among authors: prchal l. Int J Mol Sci. 2020 Mar 17;21(6):2059. doi: 10.3390/ijms21062059. Int J Mol Sci. 2020. PMID: 32192199 Free PMC article.
Wide-Antimicrobial Spectrum of Picolinium Salts.
Salajkova S, Benkova M, Marek J, Sleha R, Prchal L, Malinak D, Dolezal R, Sepčić K, Gunde-Cimerman N, Kuca K, Soukup O. Salajkova S, et al. Among authors: prchal l. Molecules. 2020 May 11;25(9):2254. doi: 10.3390/molecules25092254. Molecules. 2020. PMID: 32403238 Free PMC article.
46 results