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The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2.
Chaib S, López-Domínguez JA, Lalinde-Gutiérrez M, Prats N, Marin I, Boix O, García-Garijo A, Meyer K, Muñoz MI, Aguilera M, Mateo L, Stephan-Otto Attolini C, Llanos S, Pérez-Ramos S, Escorihuela M, Al-Shahrour F, Cash TP, Tchkonia T, Kirkland JL, Abad M, Gros A, Arribas J, Serrano M. Chaib S, et al. Among authors: prats n. Nat Cancer. 2024 Mar;5(3):448-462. doi: 10.1038/s43018-023-00712-x. Epub 2024 Jan 24. Nat Cancer. 2024. PMID: 38267628 Free PMC article.
Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype.
Maus M, López-Polo V, Mateo L, Lafarga M, Aguilera M, De Lama E, Meyer K, Sola A, Lopez-Martinez C, López-Alonso I, Guasch-Piqueras M, Hernandez-Gonzalez F, Chaib S, Rovira M, Sanchez M, Faner R, Agusti A, Diéguez-Hurtado R, Ortega S, Manonelles A, Engelhardt S, Monteiro F, Stephan-Otto Attolini C, Prats N, Albaiceta G, Cruzado JM, Serrano M. Maus M, et al. Among authors: prats n. Nat Metab. 2023 Dec;5(12):2111-2130. doi: 10.1038/s42255-023-00928-2. Epub 2023 Dec 14. Nat Metab. 2023. PMID: 38097808 Free PMC article.
Vitamin B12 is a limiting factor for induced cellular plasticity and tissue repair.
Kovatcheva M, Melendez E, Chondronasiou D, Pietrocola F, Bernad R, Caballe A, Junza A, Capellades J, Holguín-Horcajo A, Prats N, Durand S, Rovira M, Yanes O, Stephan-Otto Attolini C, Kroemer G, Serrano M. Kovatcheva M, et al. Among authors: prats n. Nat Metab. 2023 Nov;5(11):1911-1930. doi: 10.1038/s42255-023-00916-6. Epub 2023 Nov 16. Nat Metab. 2023. PMID: 37973897 Free PMC article.
Human senescent fibroblasts trigger progressive lung fibrosis in mice.
Hernandez-Gonzalez F, Prats N, Ramponi V, López-Domínguez JA, Meyer K, Aguilera M, Muñoz Martín MI, Martínez D, Agusti A, Faner R, Sellarés J, Pietrocola F, Serrano M. Hernandez-Gonzalez F, et al. Among authors: prats n. Aging (Albany NY). 2023 Jul 1;15(14):6641-6657. doi: 10.18632/aging.204825. Epub 2023 Jul 1. Aging (Albany NY). 2023. PMID: 37393107 Free PMC article.
Targeting lymphoid-derived IL-17 signaling to delay skin aging.
Solá P, Mereu E, Bonjoch J, Casado-Peláez M, Prats N, Aguilera M, Reina O, Blanco E, Esteller M, Di Croce L, Heyn H, Solanas G, Benitah SA. Solá P, et al. Among authors: prats n. Nat Aging. 2023 Jun;3(6):688-704. doi: 10.1038/s43587-023-00431-z. Epub 2023 Jun 8. Nat Aging. 2023. PMID: 37291218 Free PMC article.
Impact of the 2021 La Palma volcanic eruption on air quality: Insights from a multidisciplinary approach.
Milford C, Torres C, Vilches J, Gossman AK, Weis F, Suárez-Molina D, García OE, Prats N, Barreto Á, García RD, Bustos JJ, Marrero CL, Ramos R, Chinea N, Boulesteix T, Taquet N, Rodríguez S, López-Darias J, Sicard M, Córdoba-Jabonero C, Cuevas E. Milford C, et al. Among authors: prats n. Sci Total Environ. 2023 Apr 15;869:161652. doi: 10.1016/j.scitotenv.2023.161652. Epub 2023 Jan 21. Sci Total Environ. 2023. PMID: 36693573 Free article.
Cellular Senescence Is Immunogenic and Promotes Antitumor Immunity.
Marin I, Boix O, Garcia-Garijo A, Sirois I, Caballe A, Zarzuela E, Ruano I, Attolini CS, Prats N, López-Domínguez JA, Kovatcheva M, Garralda E, Muñoz J, Caron E, Abad M, Gros A, Pietrocola F, Serrano M. Marin I, et al. Among authors: prats n. Cancer Discov. 2023 Feb 6;13(2):410-431. doi: 10.1158/2159-8290.CD-22-0523. Cancer Discov. 2023. PMID: 36302218 Free PMC article.
Deciphering the roadmap of in vivo reprogramming toward pluripotency.
Chondronasiou D, Martínez de Villarreal J, Melendez E, Lynch CJ, Pozo ND, Kovatcheva M, Aguilera M, Prats N, Real FX, Serrano M. Chondronasiou D, et al. Among authors: prats n. Stem Cell Reports. 2022 Nov 8;17(11):2501-2517. doi: 10.1016/j.stemcr.2022.09.009. Epub 2022 Oct 20. Stem Cell Reports. 2022. PMID: 36270281 Free PMC article.
Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming.
Chondronasiou D, Gill D, Mosteiro L, Urdinguio RG, Berenguer-Llergo A, Aguilera M, Durand S, Aprahamian F, Nirmalathasan N, Abad M, Martin-Herranz DE, Stephan-Otto Attolini C, Prats N, Kroemer G, Fraga MF, Reik W, Serrano M. Chondronasiou D, et al. Among authors: prats n. Aging Cell. 2022 Mar;21(3):e13578. doi: 10.1111/acel.13578. Epub 2022 Mar 2. Aging Cell. 2022. PMID: 35235716 Free PMC article.
97 results