Prasad B - Search Results

1

Impact of CYP2C:TG Haplotype on CYP2C19 Substrates Clearance In Vivo, Protein Content, and In Vitro Activity.

Zubiaur P, Soria-Chacartegui P, Boone EC, Prasad B, Dinh J, Wang WY, Zugbi S, Rodríguez-Lopez A, González-Iglesias E, Leeder JS, Abad-Santos F, Gaedigk A. Zubiaur P, et al. Among authors: prasad b. Clin Pharmacol Ther. 2023 Nov;114(5):1033-1042. doi: 10.1002/cpt.3012. Epub 2023 Aug 11. Clin Pharmacol Ther. 2023. PMID: 37528442

2

Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism.

Ladumor MK, Bhatt DK, Gaedigk A, Sharma S, Thakur A, Pearce RE, Leeder JS, Bolger MB, Singh S, Prasad B. Ladumor MK, et al. Among authors: prasad b. Drug Metab Dispos. 2019 Aug;47(8):818-831. doi: 10.1124/dmd.119.086462. Epub 2019 May 17. Drug Metab Dispos. 2019. PMID: 31101678 Free PMC article.

3

Optimized Renal Transporter Quantification by Using Aquaporin 1 and Aquaporin 2 as Anatomical Markers: Application in Characterizing the Ontogeny of Renal Transporters and Its Correlation with Hepatic Transporters in Paired Human Samples.

Li CY, Hosey-Cojocari C, Basit A, Unadkat JD, Leeder JS, Prasad B. Li CY, et al. Among authors: prasad b. AAPS J. 2019 Jul 11;21(5):88. doi: 10.1208/s12248-019-0359-1. AAPS J. 2019. PMID: 31297641 Free PMC article.

4

Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6-Mediated Metabolic Activity.

Dalton R, Lee SB, Claw KG, Prasad B, Phillips BR, Shen DD, Wong LH, Fade M, McDonald MG, Dunham MJ, Fowler DM, Rettie AE, Schuetz E, Thornton TA, Nickerson DA, Gaedigk A, Thummel KE, Woodahl EL. Dalton R, et al. Among authors: prasad b. Clin Transl Sci. 2020 Jan;13(1):147-156. doi: 10.1111/cts.12695. Epub 2019 Oct 25. Clin Transl Sci. 2020. PMID: 31536170 Free PMC article.

5

Normalized Testosterone Glucuronide as a Potential Urinary Biomarker for Highly Variable UGT2B17 in Children 7-18 Years.

Zhang H, Basit A, Wolford C, Chen KF, Gaedigk A, Lin YS, Leeder JS, Prasad B. Zhang H, et al. Among authors: prasad b. Clin Pharmacol Ther. 2020 May;107(5):1149-1158. doi: 10.1002/cpt.1764. Epub 2020 Feb 12. Clin Pharmacol Ther. 2020. PMID: 31900930 Free PMC article.

6

Ontogeny of Drug-Metabolizing Enzymes.

Thakur A, Parvez MM, Leeder JS, Prasad B. Thakur A, et al. Among authors: prasad b. Methods Mol Biol. 2021;2342:551-593. doi: 10.1007/978-1-0716-1554-6_18. Methods Mol Biol. 2021. PMID: 34272706 Review.

7

Ontogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of Liver.

Leeder JS, Dinh JC, Gaedigk A, Staggs VS, Prasad B, Pearce RE. Leeder JS, et al. Among authors: prasad b. Drug Metab Dispos. 2022 Jan;50(1):24-32. doi: 10.1124/dmd.121.000623. Epub 2021 Oct 22. Drug Metab Dispos. 2022. PMID: 34686522 Free PMC article.

8

Interindividual Variability and Differential Tissue Abundance of Mitochondrial Amidoxime Reducing Component Enzymes in Humans.

Ahire D, Basit A, Christopher LJ, Iyer R, Leeder JS, Prasad B. Ahire D, et al. Among authors: prasad b. Drug Metab Dispos. 2022 Mar;50(3):191-196. doi: 10.1124/dmd.121.000805. Epub 2021 Dec 23. Drug Metab Dispos. 2022. PMID: 34949674 Free PMC article.

9

Cardiac Disease Alters Myocardial Tissue Levels of Epoxyeicosatrienoic Acids and Key Proteins Involved in Their Biosynthesis and Degradation.

Aliwarga T, Dinh JC, Heyward S, Prasad B, Gharib SA, Lemaitre RN, Sotoodehnia N, Totah RA. Aliwarga T, et al. Among authors: prasad b. Int J Mol Sci. 2022 Oct 17;23(20):12433. doi: 10.3390/ijms232012433. Int J Mol Sci. 2022. PMID: 36293289 Free PMC article.

10

Sex and the Kidney Drug-Metabolizing Enzymes and Transporters: Are Preclinical Drug Disposition Data Translatable to Humans?

Thakur A, Yue G, Ahire D, Mettu VS, Al Maghribi A, Ford K, Peixoto L, Leeder JS, Prasad B. Thakur A, et al. Among authors: prasad b. Clin Pharmacol Ther. 2024 May 6. doi: 10.1002/cpt.3277. Online ahead of print. Clin Pharmacol Ther. 2024. PMID: 38711199

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