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Page 1
Triterpenoid Hydroxamates as HIF Prolyl Hydrolase Inhibitors.
Minassi A, Rogati F, Cruz C, Prados ME, Galera N, Jinénez C, Appendino G, Bellido ML, Calzado MA, Caprioglio D, Muñoz E. Minassi A, et al. Among authors: prados me. J Nat Prod. 2018 Oct 26;81(10):2235-2243. doi: 10.1021/acs.jnatprod.8b00514. Epub 2018 Oct 10. J Nat Prod. 2018. PMID: 30350996
Isomeric O-methyl cannabidiolquinones with dual BACH1/NRF2 activity.
Casares L, Unciti-Broceta JD, Prados ME, Caprioglio D, Mattoteia D, Higgins M, Apendino G, Dinkova-Kostova AT, Muñoz E, de la Vega L. Casares L, et al. Among authors: prados me. Redox Biol. 2020 Oct;37:101689. doi: 10.1016/j.redox.2020.101689. Epub 2020 Aug 22. Redox Biol. 2020. PMID: 32863231 Free PMC article.
Betulinic Acid Hydroxamate is Neuroprotective and Induces Protein Phosphatase 2A-Dependent HIF-1α Stabilization and Post-transcriptional Dephosphorylation of Prolyl Hydrolase 2.
Prados ME, Correa-Sáez A, Unciti-Broceta JD, Garrido-Rodríguez M, Jimenez-Jimenez C, Mazzone M, Minassi A, Appendino G, Calzado MA, Muñoz E. Prados ME, et al. Neurotherapeutics. 2021 Jul;18(3):1849-1861. doi: 10.1007/s13311-021-01089-4. Epub 2021 Aug 2. Neurotherapeutics. 2021. PMID: 34339019 Free PMC article.
EHP-101 alleviates angiotensin II-induced fibrosis and inflammation in mice.
García-Martín A, Navarrete C, Garrido-Rodríguez M, Prados ME, Caprioglio D, Appendino G, Muñoz E. García-Martín A, et al. Among authors: prados me. Biomed Pharmacother. 2021 Oct;142:112007. doi: 10.1016/j.biopha.2021.112007. Epub 2021 Aug 9. Biomed Pharmacother. 2021. PMID: 34385107 Free article.
A cannabidiol aminoquinone derivative activates the PP2A/B55α/HIF pathway and shows protective effects in a murine model of traumatic brain injury.
Navarrete C, García-Martín A, Correa-Sáez A, Prados ME, Fernández F, Pineda R, Mazzone M, Álvarez-Benito M, Calzado MA, Muñoz E. Navarrete C, et al. Among authors: prados me. J Neuroinflammation. 2022 Jul 9;19(1):177. doi: 10.1186/s12974-022-02540-9. J Neuroinflammation. 2022. PMID: 35810304 Free PMC article.
Cannabidiol markedly alleviates skin and liver fibrosis.
Del Río C, Ruiz-Pino F, Prados ME, Fiebich BL, Tena-Sempere M, Muñoz E. Del Río C, et al. Among authors: prados me. Front Pharmacol. 2022 Oct 19;13:981817. doi: 10.3389/fphar.2022.981817. eCollection 2022. Front Pharmacol. 2022. PMID: 36339540 Free PMC article.
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