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Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.
Prévost J, Chen Y, Zhou F, Tolbert WD, Gasser R, Medjahed H, Nayrac M, Nguyen DN, Gottumukkala S, Hessell AJ, Rao VB, Pozharski E, Huang RK, Matthies D, Finzi A, Pazgier M. Prévost J, et al. Among authors: pozharski e. Nat Commun. 2023 Oct 23;14(1):6710. doi: 10.1038/s41467-023-42500-2. Nat Commun. 2023. PMID: 37872202 Free PMC article.
A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection.
Beaudoin-Bussières G, Chen Y, Ullah I, Prévost J, Tolbert WD, Symmes K, Ding S, Benlarbi M, Gong SY, Tauzin A, Gasser R, Chatterjee D, Vézina D, Goyette G, Richard J, Zhou F, Stamatatos L, McGuire AT, Charest H, Roger M, Pozharski E, Kumar P, Mothes W, Uchil PD, Pazgier M, Finzi A. Beaudoin-Bussières G, et al. Among authors: pozharski e. Cell Rep. 2022 Feb 15;38(7):110368. doi: 10.1016/j.celrep.2022.110368. Epub 2022 Jan 25. Cell Rep. 2022. PMID: 35123652 Free PMC article.
Structural and functional analysis of the pro-domain of human cathelicidin, LL-37.
Pazgier M, Ericksen B, Ling M, Toth E, Shi J, Li X, Galliher-Beckley A, Lan L, Zou G, Zhan C, Yuan W, Pozharski E, Lu W. Pazgier M, et al. Among authors: pozharski e. Biochemistry. 2013 Mar 5;52(9):1547-58. doi: 10.1021/bi301008r. Epub 2013 Feb 21. Biochemistry. 2013. PMID: 23406372 Free PMC article.
Structure of extracellular signal-regulated kinase 2 in complex with ATP and ADP.
Zhang J, Shapiro P, Pozharski E. Zhang J, et al. Among authors: pozharski e. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1434-9. doi: 10.1107/S1744309112042972. Epub 2012 Nov 14. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 23192020 Free PMC article.
X-ray crystal structure of human calcium-bound S100A1.
Melville Z, Aligholizadeh E, McKnight LE, Weber DJ, Pozharski E, Weber DJ. Melville Z, et al. Among authors: pozharski e. Acta Crystallogr F Struct Biol Commun. 2017 Apr 1;73(Pt 4):215-221. doi: 10.1107/S2053230X17003983. Epub 2017 Mar 22. Acta Crystallogr F Struct Biol Commun. 2017. PMID: 28368280 Free PMC article.
Crystal Structure of a Bivalent Antibody Fab Fragment.
Shahid S, Gao M, Travis Gallagher D, Pozharski E, Brinson RG, Keck ZY, Foung SKH, Fuerst TR, Mariuzza RA. Shahid S, et al. Among authors: pozharski e. J Mol Biol. 2021 Jan 22;433(2):166714. doi: 10.1016/j.jmb.2020.11.013. Epub 2020 Nov 19. J Mol Biol. 2021. PMID: 33220264
Divalent metal ion complexes of S100B in the absence and presence of pentamidine.
Charpentier TH, Wilder PT, Liriano MA, Varney KM, Pozharski E, MacKerell AD Jr, Coop A, Toth EA, Weber DJ. Charpentier TH, et al. Among authors: pozharski e. J Mol Biol. 2008 Sep 26;382(1):56-73. doi: 10.1016/j.jmb.2008.06.047. Epub 2008 Jun 24. J Mol Biol. 2008. PMID: 18602402 Free PMC article.
Characterizing inhibitors of human AP endonuclease 1.
Pidugu LS, Servius HW, Sevdalis SE, Cook ME, Varney KM, Pozharski E, Drohat AC. Pidugu LS, et al. Among authors: pozharski e. PLoS One. 2023 Jan 18;18(1):e0280526. doi: 10.1371/journal.pone.0280526. eCollection 2023. PLoS One. 2023. PMID: 36652434 Free PMC article.
77 results