Pozharski E - Search Results

1

Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies.

Metcalf MC, Janus BM, Yin R, Wang R, Guest JD, Pozharski E, Law M, Mariuzza RA, Toth EA, Pierce BG, Fuerst TR, Ofek G. Metcalf MC, et al. Among authors: pozharski e. Nat Commun. 2023 Jul 5;14(1):3980. doi: 10.1038/s41467-023-39659-z. Nat Commun. 2023. PMID: 37407593 Free PMC article.

2

Divalent metal ion complexes of S100B in the absence and presence of pentamidine.

Charpentier TH, Wilder PT, Liriano MA, Varney KM, Pozharski E, MacKerell AD Jr, Coop A, Toth EA, Weber DJ. Charpentier TH, et al. Among authors: pozharski e. J Mol Biol. 2008 Sep 26;382(1):56-73. doi: 10.1016/j.jmb.2008.06.047. Epub 2008 Jun 24. J Mol Biol. 2008. PMID: 18602402 Free PMC article.

3

Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography.

Charpentier TH, Wilder PT, Liriano MA, Varney KM, Zhong S, Coop A, Pozharski E, MacKerell AD Jr, Toth EA, Weber DJ. Charpentier TH, et al. Among authors: pozharski e. Biochemistry. 2009 Jul 7;48(26):6202-12. doi: 10.1021/bi9005754. Biochemistry. 2009. PMID: 19469484 Free PMC article.

4

The effects of CapZ peptide (TRTK-12) binding to S100B-Ca2+ as examined by NMR and X-ray crystallography.

Charpentier TH, Thompson LE, Liriano MA, Varney KM, Wilder PT, Pozharski E, Toth EA, Weber DJ. Charpentier TH, et al. Among authors: pozharski e. J Mol Biol. 2010 Mar 12;396(5):1227-43. doi: 10.1016/j.jmb.2009.12.057. Epub 2010 Jan 4. J Mol Biol. 2010. PMID: 20053360 Free PMC article.

5

In vitro screening and structural characterization of inhibitors of the S100B-p53 interaction.

Wilder PT, Charpentier TH, Liriano MA, Gianni K, Varney KM, Pozharski E, Coop A, Toth EA, Mackerell AD, Weber DJ. Wilder PT, et al. Among authors: pozharski e. Int J High Throughput Screen. 2010 Jul 7;2010(1):109-126. doi: 10.2147/IJHTS.S8210. Int J High Throughput Screen. 2010. PMID: 21132089 Free PMC article.

6

Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg2+ cofactor.

Manvilla BA, Pozharski E, Toth EA, Drohat AC. Manvilla BA, et al. Among authors: pozharski e. Acta Crystallogr D Biol Crystallogr. 2013 Dec;69(Pt 12):2555-62. doi: 10.1107/S0907444913027042. Epub 2013 Nov 19. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 24311596 Free PMC article.

7

A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone.

Pidugu LS, Mbimba JC, Ahmad M, Pozharski E, Sausville EA, Emadi A, Toth EA. Pidugu LS, et al. Among authors: pozharski e. BMC Struct Biol. 2016 Jan 28;16:1. doi: 10.1186/s12900-016-0052-x. BMC Struct Biol. 2016. PMID: 26822308 Free PMC article.

8

Crystal structures of human 3-hydroxyanthranilate 3,4-dioxygenase with native and non-native metals bound in the active site.

Pidugu LS, Neu H, Wong TL, Pozharski E, Molloy JL, Michel SL, Toth EA. Pidugu LS, et al. Among authors: pozharski e. Acta Crystallogr D Struct Biol. 2017 Apr 1;73(Pt 4):340-348. doi: 10.1107/S2059798317002029. Epub 2017 Mar 31. Acta Crystallogr D Struct Biol. 2017. PMID: 28375145 Free PMC article.

9

Crystal Structure of a Bivalent Antibody Fab Fragment.

Shahid S, Gao M, Travis Gallagher D, Pozharski E, Brinson RG, Keck ZY, Foung SKH, Fuerst TR, Mariuzza RA. Shahid S, et al. Among authors: pozharski e. J Mol Biol. 2021 Jan 22;433(2):166714. doi: 10.1016/j.jmb.2020.11.013. Epub 2020 Nov 19. J Mol Biol. 2021. PMID: 33220264

10

Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.

Prévost J, Chen Y, Zhou F, Tolbert WD, Gasser R, Medjahed H, Nayrac M, Nguyen DN, Gottumukkala S, Hessell AJ, Rao VB, Pozharski E, Huang RK, Matthies D, Finzi A, Pazgier M. Prévost J, et al. Among authors: pozharski e. Nat Commun. 2023 Oct 23;14(1):6710. doi: 10.1038/s41467-023-42500-2. Nat Commun. 2023. PMID: 37872202 Free PMC article.

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