Powers GD - Search Results

1

Human and non-human primate intestinal FcRn expression and immunoglobulin G transcytosis.

Hornby PJ, Cooper PR, Kliwinski C, Ragwan E, Mabus JR, Harman B, Thompson S, Kauffman AL, Yan Z, Tam SH, Dorai H, Powers GD, Giles-Komar J. Hornby PJ, et al. Among authors: powers gd. Pharm Res. 2014 Apr;31(4):908-22. doi: 10.1007/s11095-013-1212-3. Epub 2013 Sep 26. Pharm Res. 2014. PMID: 24072267 Free PMC article.

2

Contribution of FcRn binding to intestinal uptake of IgG in suckling rat pups and human FcRn-transgenic mice.

Kliwinski C, Cooper PR, Perkinson R, Mabus JR, Tam SH, Wilkinson TM, Giles-Komar J, Scallon B, Powers GD, Hornby PJ. Kliwinski C, et al. Among authors: powers gd. Am J Physiol Gastrointest Liver Physiol. 2013 Feb 1;304(3):G262-70. doi: 10.1152/ajpgi.00340.2012. Epub 2012 Dec 6. Am J Physiol Gastrointest Liver Physiol. 2013. PMID: 23220220 Free article.

3

The contribution of cell surface FcRn in monoclonal antibody serum uptake from the intestine in suckling rat pups.

Cooper PR, Kliwinski CM, Perkinson RA, Ragwan E, Mabus JR, Powers GD, Dorai H, Giles-Komar J, Hornby PJ. Cooper PR, et al. Among authors: powers gd. Front Pharmacol. 2014 Oct 7;5:225. doi: 10.3389/fphar.2014.00225. eCollection 2014. Front Pharmacol. 2014. PMID: 25339905 Free PMC article.

4

Tumor-associated and microbial proteases compromise host IgG effector functions by a single cleavage proximal to the hinge.

Brezski RJ, Vafa O, Petrone D, Tam SH, Powers G, Ryan MH, Luongo JL, Oberholtzer A, Knight DM, Jordan RE. Brezski RJ, et al. Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17864-9. doi: 10.1073/pnas.0904174106. Epub 2009 Oct 7. Proc Natl Acad Sci U S A. 2009. PMID: 19815504 Free PMC article.

5

A rapid method for generating and characterizing anti-variable region monoclonal antibodies.

Staquet K, Kwok D, Rycyzyn MA, Petley T, Lacy ER, Powers G, Giles-Komar J. Staquet K, et al. Hum Antibodies. 2006;15(4):155-62. Hum Antibodies. 2006. PMID: 17522437

6

Development and utilization of activated STAT3 detection assays for screening a library of secreted proteins.

Fursov N, Gates IV, Panavas T, Giles-Komar J, Powers G. Fursov N, et al. Assay Drug Dev Technol. 2011 Aug;9(4):420-9. doi: 10.1089/adt.2010.0348. Epub 2011 Feb 6. Assay Drug Dev Technol. 2011. PMID: 21294636

7

Generation and characterization of rat anti-mouse ST2L monoclonal antibodies.

Fursov N, Johnston E, Duffy K, Cotty A, Petley T, Fisher J, Jiang H, Rycyzyn MA, Giles-Komar J, Powers G. Fursov N, et al. Hybridoma (Larchmt). 2011 Apr;30(2):153-62. doi: 10.1089/hyb.2010.0100. Hybridoma (Larchmt). 2011. PMID: 21529288

8

Generation and evaluation of mammalian secreted and membrane protein expression libraries for high-throughput target discovery.

Panavas T, Lu J, Liu X, Winkis AM, Powers G, Naso MF, Amegadzie B. Panavas T, et al. Protein Expr Purif. 2011 Sep;79(1):7-15. doi: 10.1016/j.pep.2011.05.011. Epub 2011 May 26. Protein Expr Purif. 2011. PMID: 21640830

9

Discovery and pharmacological characterization of cetrelimab (JNJ-63723283), an anti-programmed cell death protein-1 (PD-1) antibody, in human cancer models.

DeAngelis N, Ferrante C, Powers G, Sendecki J, Mattson B, Pizutti D, Packman K, Wang W, Trouba K, Nanjunda R, Wheeler J, Brittingham R, Wu SJ, Luo J, Lorenzi MV, Verona RI. DeAngelis N, et al. Cancer Chemother Pharmacol. 2022 Apr;89(4):515-527. doi: 10.1007/s00280-022-04415-5. Epub 2022 Mar 17. Cancer Chemother Pharmacol. 2022. PMID: 35298699 Free PMC article.

10

Pharmacology and placental transfer of a human alphav integrin monoclonal antibody in rabbits.

Martin PL, Zhou Z, Van den Bulck K, Kwok D, Powers G, Jiao Q, Schantz A, Treacy G. Martin PL, et al. Birth Defects Res B Dev Reprod Toxicol. 2010 Apr;89(2):116-23. doi: 10.1002/bdrb.20232. Birth Defects Res B Dev Reprod Toxicol. 2010. PMID: 20151458

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