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Mice Lacking Gpr75 are Hypophagic and Thin.
Powell DR, Doree DD, DaCosta CM, Platt KA, Brommage R, Buhring L, Revelli JP, Shadoan MK. Powell DR, et al. Diabetes Metab Syndr Obes. 2022 Jan 5;15:45-58. doi: 10.2147/DMSO.S342799. eCollection 2022. Diabetes Metab Syndr Obes. 2022. PMID: 35023939 Free PMC article.
High-Throughput Screening of Mouse Gene Knockouts Identifies Established and Novel High Body Fat Phenotypes.
Powell DR, Revelli JP, Doree DD, DaCosta CM, Desai U, Shadoan MK, Rodriguez L, Mullens M, Yang QM, Ding ZM, Kirkpatrick LL, Vogel P, Zambrowicz B, Sands AT, Platt KA, Hansen GM, Brommage R. Powell DR, et al. Diabetes Metab Syndr Obes. 2021 Aug 28;14:3753-3785. doi: 10.2147/DMSO.S322083. eCollection 2021. Diabetes Metab Syndr Obes. 2021. PMID: 34483672 Free PMC article.
Improved glycemic control in mice lacking Sglt1 and Sglt2.
Powell DR, DaCosta CM, Gay J, Ding ZM, Smith M, Greer J, Doree D, Jeter-Jones S, Mseeh F, Rodriguez LA, Harris A, Buhring L, Platt KA, Vogel P, Brommage R, Shadoan MK, Sands AT, Zambrowicz B. Powell DR, et al. Am J Physiol Endocrinol Metab. 2013 Jan 15;304(2):E117-30. doi: 10.1152/ajpendo.00439.2012. Epub 2012 Nov 13. Am J Physiol Endocrinol Metab. 2013. PMID: 23149623 Free article.
Effect of LX4211 on glucose homeostasis and body composition in preclinical models.
Powell DR, DaCosta CM, Smith M, Doree D, Harris A, Buhring L, Heydorn W, Nouraldeen A, Xiong W, Yalamanchili P, Mseeh F, Wilson A, Shadoan M, Zambrowicz B, Ding ZM. Powell DR, et al. J Pharmacol Exp Ther. 2014 Aug;350(2):232-42. doi: 10.1124/jpet.114.214304. Epub 2014 May 21. J Pharmacol Exp Ther. 2014. PMID: 24849925
Fatty acid desaturase 1 knockout mice are lean with improved glycemic control and decreased development of atheromatous plaque.
Powell DR, Gay JP, Smith M, Wilganowski N, Harris A, Holland A, Reyes M, Kirkham L, Kirkpatrick LL, Zambrowicz B, Hansen G, Platt KA, van Sligtenhorst I, Ding ZM, Desai U. Powell DR, et al. Diabetes Metab Syndr Obes. 2016 Jun 22;9:185-99. doi: 10.2147/DMSO.S106653. eCollection 2016. Diabetes Metab Syndr Obes. 2016. PMID: 27382320 Free PMC article.
High-throughput screening of mouse knockout lines identifies true lean and obese phenotypes.
Brommage R, Desai U, Revelli JP, Donoviel DB, Fontenot GK, Dacosta CM, Smith DD, Kirkpatrick LL, Coker KJ, Donoviel MS, Eberhart DE, Holt KH, Kelly MR, Paradee WJ, Philips AV, Platt KA, Suwanichkul A, Hansen GM, Sands AT, Zambrowicz BP, Powell DR. Brommage R, et al. Among authors: powell dr. Obesity (Silver Spring). 2008 Oct;16(10):2362-7. doi: 10.1038/oby.2008.361. Epub 2008 Jul 31. Obesity (Silver Spring). 2008. PMID: 18719666 Free article.
Profound obesity secondary to hyperphagia in mice lacking kinase suppressor of ras 2.
Revelli JP, Smith D, Allen J, Jeter-Jones S, Shadoan MK, Desai U, Schneider M, van Sligtenhorst I, Kirkpatrick L, Platt KA, Suwanichkul A, Savelieva K, Gerhardt B, Mitchell J, Syrewicz J, Zambrowicz B, Hamman BD, Vogel P, Powell DR. Revelli JP, et al. Among authors: powell dr. Obesity (Silver Spring). 2011 May;19(5):1010-8. doi: 10.1038/oby.2010.282. Epub 2010 Dec 2. Obesity (Silver Spring). 2011. PMID: 21127480 Free article.
425 results