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PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation.
Gulluni F, Prever L, Li H, Krafcikova P, Corrado I, Lo WT, Margaria JP, Chen A, De Santis MC, Cnudde SJ, Fogerty J, Yuan A, Massarotti A, Sarijalo NT, Vadas O, Williams RL, Thelen M, Powell DR, Schueler M, Wiesener MS, Balla T, Baris HN, Tiosano D, McDermott BM Jr, Perkins BD, Ghigo A, Martini M, Haucke V, Boura E, Merlo GR, Buchner DA, Hirsch E. Gulluni F, et al. Among authors: powell dr. Science. 2021 Dec 10;374(6573):eabk0410. doi: 10.1126/science.abk0410. Epub 2021 Dec 10. Science. 2021. PMID: 34882480 Free PMC article.
High-Throughput Screening of Mouse Gene Knockouts Identifies Established and Novel High Body Fat Phenotypes.
Powell DR, Revelli JP, Doree DD, DaCosta CM, Desai U, Shadoan MK, Rodriguez L, Mullens M, Yang QM, Ding ZM, Kirkpatrick LL, Vogel P, Zambrowicz B, Sands AT, Platt KA, Hansen GM, Brommage R. Powell DR, et al. Diabetes Metab Syndr Obes. 2021 Aug 28;14:3753-3785. doi: 10.2147/DMSO.S322083. eCollection 2021. Diabetes Metab Syndr Obes. 2021. PMID: 34483672 Free PMC article.
Mice Lacking Gpr75 are Hypophagic and Thin.
Powell DR, Doree DD, DaCosta CM, Platt KA, Brommage R, Buhring L, Revelli JP, Shadoan MK. Powell DR, et al. Diabetes Metab Syndr Obes. 2022 Jan 5;15:45-58. doi: 10.2147/DMSO.S342799. eCollection 2022. Diabetes Metab Syndr Obes. 2022. PMID: 35023939 Free PMC article.
Diacylglycerol Lipase α Knockout Mice Demonstrate Metabolic and Behavioral Phenotypes Similar to Those of Cannabinoid Receptor 1 Knockout Mice.
Powell DR, Gay JP, Wilganowski N, Doree D, Savelieva KV, Lanthorn TH, Read R, Vogel P, Hansen GM, Brommage R, Ding ZM, Desai U, Zambrowicz B. Powell DR, et al. Front Endocrinol (Lausanne). 2015 Jun 2;6:86. doi: 10.3389/fendo.2015.00086. eCollection 2015. Front Endocrinol (Lausanne). 2015. PMID: 26082754 Free PMC article.
Effects of LX4211, a dual sodium-dependent glucose cotransporters 1 and 2 inhibitor, on postprandial glucose, insulin, glucagon-like peptide 1, and peptide tyrosine tyrosine in a dose-timing study in healthy subjects.
Zambrowicz B, Ogbaa I, Frazier K, Banks P, Turnage A, Freiman J, Boehm KA, Ruff D, Powell D, Sands A. Zambrowicz B, et al. Clin Ther. 2013 Aug;35(8):1162-1173.e8. doi: 10.1016/j.clinthera.2013.06.011. Epub 2013 Jul 31. Clin Ther. 2013. PMID: 23911260 Clinical Trial.
425 results