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Hydroxyurea therapy modulates sickle cell anemia red blood cell physiology: Impact on RBC deformability, oxidative stress, nitrite levels and nitric oxide synthase signalling pathway.
Nader E, Grau M, Fort R, Collins B, Cannas G, Gauthier A, Walpurgis K, Martin C, Bloch W, Poutrel S, Hot A, Renoux C, Thevis M, Joly P, Romana M, Guillot N, Connes P. Nader E, et al. Among authors: poutrel s. Nitric Oxide. 2018 Dec 1;81:28-35. doi: 10.1016/j.niox.2018.10.003. Epub 2018 Oct 19. Nitric Oxide. 2018. PMID: 30342855 Clinical Trial.
Automatic depletion with Spectra Optia allows a safe 16% reduction of red blood cell pack consumption in exchanged sickle cell anemia patients.
Hequet O, Poutrel S, Connes P, Revesz D, Chelghoum Y, Kebaili K, Cannas G, Gauthier A, Guironnet-Paquet A, Vocanson M, Nicolas JF, Renoux C, Raba M, Cognasse F, Bertrand Y, Hot A, Joly P. Hequet O, et al. Among authors: poutrel s. Transfusion. 2019 May;59(5):1692-1697. doi: 10.1111/trf.15188. Epub 2019 Feb 12. Transfusion. 2019. PMID: 30747440
Effects of Genotypes and Treatment on Oxygenscan Parameters in Sickle Cell Disease.
Boisson C, Rab MAE, Nader E, Renoux C, Kanne C, Bos J, van Oirschot BA, Joly P, Fort R, Gauthier A, Stauffer E, Poutrel S, Kebaili K, Cannas G, Garnier N, Renard C, Hequet O, Hot A, Bertrand Y, van Wijk R, Sheehan VA, van Beers EJ, Connes P. Boisson C, et al. Among authors: poutrel s. Cells. 2021 Apr 5;10(4):811. doi: 10.3390/cells10040811. Cells. 2021. PMID: 33916502 Free PMC article.
Comparisons of oxygen gradient ektacytometry parameters between sickle cell patients with or without α-thalassaemia.
Boisson C, Renoux C, Nader E, Gauthier A, Poutrel S, Rab M, Fort R, Bertrand Y, Stauffer E, Cannas G, Kebaili K, Virot E, Hot A, Sheehan V, van Beers E, van Wijk R, Joly P, Connes P. Boisson C, et al. Among authors: poutrel s. Br J Haematol. 2021 Nov;195(4):629-633. doi: 10.1111/bjh.17777. Epub 2021 Aug 15. Br J Haematol. 2021. PMID: 34396507
Nocturnal Hypoxemia Rather Than Obstructive Sleep Apnea Is Associated With Decreased Red Blood Cell Deformability and Enhanced Hemolysis in Patients With Sickle Cell Disease.
Stauffer E, Poutrel S, Cannas G, Gauthier A, Fort R, Bertrand Y, Renoux C, Joly P, Boisson C, Hot A, Peter-Derex L, Pialoux V, PetitJean T, Connes P. Stauffer E, et al. Among authors: poutrel s. Front Physiol. 2021 Sep 24;12:743399. doi: 10.3389/fphys.2021.743399. eCollection 2021. Front Physiol. 2021. PMID: 34630163 Free PMC article.
Increased blood viscosity and red blood cell aggregation in patients with COVID-19.
Nader E, Nougier C, Boisson C, Poutrel S, Catella J, Martin F, Charvet J, Girard S, Havard-Guibert S, Martin M, Rezigue H, Desmurs-Clavel H, Renoux C, Joly P, Guillot N, Bertrand Y, Hot A, Dargaud Y, Connes P. Nader E, et al. Among authors: poutrel s. Am J Hematol. 2022 Mar 1;97(3):283-292. doi: 10.1002/ajh.26440. Epub 2021 Dec 23. Am J Hematol. 2022. PMID: 34939698 Free article.
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