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Drug resistance and treatment failure in leishmaniasis: A 21st century challenge.
Ponte-Sucre A, Gamarro F, Dujardin JC, Barrett MP, López-Vélez R, García-Hernández R, Pountain AW, Mwenechanya R, Papadopoulou B. Ponte-Sucre A, et al. Among authors: pountain aw. PLoS Negl Trop Dis. 2017 Dec 14;11(12):e0006052. doi: 10.1371/journal.pntd.0006052. eCollection 2017 Dec. PLoS Negl Trop Dis. 2017. PMID: 29240765 Free PMC article. Review.
Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana.
Mwenechanya R, Kovářová J, Dickens NJ, Mudaliar M, Herzyk P, Vincent IM, Weidt SK, Burgess KE, Burchmore RJS, Pountain AW, Smith TK, Creek DJ, Kim DH, Lepesheva GI, Barrett MP. Mwenechanya R, et al. Among authors: pountain aw. PLoS Negl Trop Dis. 2017 Jun 16;11(6):e0005649. doi: 10.1371/journal.pntd.0005649. eCollection 2017 Jun. PLoS Negl Trop Dis. 2017. PMID: 28622334 Free PMC article.
Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response.
Alpizar-Sosa EA, Ithnin NRB, Wei W, Pountain AW, Weidt SK, Donachie AM, Ritchie R, Dickie EA, Burchmore RJS, Denny PW, Barrett MP. Alpizar-Sosa EA, et al. Among authors: pountain aw. PLoS Negl Trop Dis. 2022 Sep 28;16(9):e0010779. doi: 10.1371/journal.pntd.0010779. eCollection 2022 Sep. PLoS Negl Trop Dis. 2022. PMID: 36170238 Free PMC article.
Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs.
Giordani F, Paape D, Vincent IM, Pountain AW, Fernández-Cortés F, Rico E, Zhang N, Morrison LJ, Freund Y, Witty MJ, Peter R, Edwards DY, Wilkes JM, van der Hooft JJJ, Regnault C, Read KD, Horn D, Field MC, Barrett MP. Giordani F, et al. Among authors: pountain aw. PLoS Pathog. 2020 Nov 3;16(11):e1008932. doi: 10.1371/journal.ppat.1008932. eCollection 2020 Nov. PLoS Pathog. 2020. PMID: 33141865 Free PMC article.
16 results