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The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex.
Koo CZ, Harrison N, Noy PJ, Szyroka J, Matthews AL, Hsia HE, Müller SA, Tüshaus J, Goulding J, Willis K, Apicella C, Cragoe B, Davis E, Keles M, Malinova A, McFarlane TA, Morrison PR, Nguyen HTH, Sykes MC, Ahmed H, Di Maio A, Seipold L, Saftig P, Cull E, Pliotas C, Rubinstein E, Poulter NS, Briddon SJ, Holliday ND, Lichtenthaler SF, Tomlinson MG. Koo CZ, et al. Among authors: poulter ns. J Biol Chem. 2020 Sep 4;295(36):12822-12839. doi: 10.1074/jbc.RA120.012601. Epub 2020 Feb 28. J Biol Chem. 2020. PMID: 32111735 Free PMC article.
RhoJ interacts with the GIT-PIX complex and regulates focal adhesion disassembly.
Wilson E, Leszczynska K, Poulter NS, Edelmann F, Salisbury VA, Noy PJ, Bacon A, Rappoport JZ, Heath JK, Bicknell R, Heath VL. Wilson E, et al. Among authors: poulter ns. J Cell Sci. 2014 Jul 15;127(Pt 14):3039-51. doi: 10.1242/jcs.140434. Epub 2014 Jun 13. J Cell Sci. 2014. PMID: 24928894 Free PMC article.
Tetraspanin Tspan9 regulates platelet collagen receptor GPVI lateral diffusion and activation.
Haining EJ, Matthews AL, Noy PJ, Romanska HM, Harris HJ, Pike J, Morowski M, Gavin RL, Yang J, Milhiet PE, Berditchevski F, Nieswandt B, Poulter NS, Watson SP, Tomlinson MG. Haining EJ, et al. Among authors: poulter ns. Platelets. 2017 Nov;28(7):629-642. doi: 10.1080/09537104.2016.1254175. Epub 2016 Dec 29. Platelets. 2017. PMID: 28032533 Free PMC article.
Evidence that GPVI is Expressed as a Mixture of Monomers and Dimers, and that the D2 Domain is not Essential for GPVI Activation.
Clark JC, Neagoe RAI, Zuidscherwoude M, Kavanagh DM, Slater A, Martin EM, Soave M, Stegner D, Nieswandt B, Poulter NS, Hummert J, Herten DP, Tomlinson MG, Hill SJ, Watson SP. Clark JC, et al. Among authors: poulter ns. Thromb Haemost. 2021 Nov;121(11):1435-1447. doi: 10.1055/a-1401-5014. Epub 2021 Apr 14. Thromb Haemost. 2021. PMID: 33638140
Syk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells.
Pollitt AY, Poulter NS, Gitz E, Navarro-Nuñez L, Wang YJ, Hughes CE, Thomas SG, Nieswandt B, Douglas MR, Owen DM, Jackson DG, Dustin ML, Watson SP. Pollitt AY, et al. Among authors: poulter ns. J Biol Chem. 2014 Dec 26;289(52):35695-710. doi: 10.1074/jbc.M114.584284. Epub 2014 Nov 3. J Biol Chem. 2014. PMID: 25368330 Free PMC article.
Low-dose Btk inhibitors selectively block platelet activation by CLEC-2.
Nicolson PLR, Nock SH, Hinds J, Garcia-Quintanilla L, Smith CW, Campos J, Brill A, Pike JA, Khan AO, Poulter NS, Kavanagh DM, Watson S, Watson CN, Clifford H, Huissoon AP, Pollitt AY, Eble JA, Pratt G, Watson SP, Hughes CE. Nicolson PLR, et al. Among authors: poulter ns. Haematologica. 2021 Jan 1;106(1):208-219. doi: 10.3324/haematol.2019.218545. Haematologica. 2021. PMID: 31949019 Free PMC article.
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