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Modulation of P2X3 and P2X2/3 Receptors by Monoclonal Antibodies.
Shcherbatko A, Foletti D, Poulsen K, Strop P, Zhu G, Hasa-Moreno A, Melton Witt J, Loo C, Krimm S, Pios A, Yu J, Brown C, Lee JK, Stroud R, Rajpal A, Shelton D. Shcherbatko A, et al. Among authors: poulsen k. J Biol Chem. 2016 Jun 3;291(23):12254-70. doi: 10.1074/jbc.M116.722330. Epub 2016 Apr 20. J Biol Chem. 2016. PMID: 27129281 Free PMC article.
Effect of attachment site on stability of cleavable antibody drug conjugates.
Dorywalska M, Strop P, Melton-Witt JA, Hasa-Moreno A, Farias SE, Galindo Casas M, Delaria K, Lui V, Poulsen K, Loo C, Krimm S, Bolton G, Moine L, Dushin R, Tran TT, Liu SH, Rickert M, Foletti D, Shelton DL, Pons J, Rajpal A. Dorywalska M, et al. Among authors: poulsen k. Bioconjug Chem. 2015 Apr 15;26(4):650-9. doi: 10.1021/bc5005747. Epub 2015 Feb 20. Bioconjug Chem. 2015. PMID: 25643134
Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy.
Dorywalska M, Strop P, Melton-Witt JA, Hasa-Moreno A, Farias SE, Galindo Casas M, Delaria K, Lui V, Poulsen K, Sutton J, Bolton G, Zhou D, Moine L, Dushin R, Tran TT, Liu SH, Rickert M, Foletti D, Shelton DL, Pons J, Rajpal A. Dorywalska M, et al. Among authors: poulsen k. PLoS One. 2015 Jul 10;10(7):e0132282. doi: 10.1371/journal.pone.0132282. eCollection 2015. PLoS One. 2015. PMID: 26161543 Free PMC article.
Site-specific conjugation improves therapeutic index of antibody drug conjugates with high drug loading.
Strop P, Delaria K, Foletti D, Witt JM, Hasa-Moreno A, Poulsen K, Casas MG, Dorywalska M, Farias S, Pios A, Lui V, Dushin R, Zhou D, Navaratnam T, Tran TT, Sutton J, Lindquist KC, Han B, Liu SH, Shelton DL, Pons J, Rajpal A. Strop P, et al. Among authors: poulsen k. Nat Biotechnol. 2015 Jul;33(7):694-6. doi: 10.1038/nbt.3274. Nat Biotechnol. 2015. PMID: 26154005 No abstract available.
Artemin has potent neurotrophic actions on injured C-fibres.
Bennett DL, Boucher TJ, Michael GJ, Popat RJ, Malcangio M, Averill SA, Poulsen KT, Priestley JV, Shelton DL, McMahon SB. Bennett DL, et al. J Peripher Nerv Syst. 2006 Dec;11(4):330-45. doi: 10.1111/j.1529-8027.2006.00106.x. J Peripher Nerv Syst. 2006. PMID: 17117942
A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor.
Klein RD, Sherman D, Ho WH, Stone D, Bennett GL, Moffat B, Vandlen R, Simmons L, Gu Q, Hongo JA, Devaux B, Poulsen K, Armanini M, Nozaki C, Asai N, Goddard A, Phillips H, Henderson CE, Takahashi M, Rosenthal A. Klein RD, et al. Among authors: poulsen k. Nature. 1997 Jun 12;387(6634):717-21. doi: 10.1038/42722. Nature. 1997. PMID: 9192898
An Optimized Full-Length FLT3/CD3 Bispecific Antibody Demonstrates Potent Anti-leukemia Activity and Reversible Hematological Toxicity.
Yeung YA, Krishnamoorthy V, Dettling D, Sommer C, Poulsen K, Ni I, Pham A, Chen W, Liao-Chan S, Lindquist K, Chin SM, Chunyk AG, Hu W, Sasu B, Chaparro-Riggers J, Djuretic I. Yeung YA, et al. Among authors: poulsen k. Mol Ther. 2020 Mar 4;28(3):889-900. doi: 10.1016/j.ymthe.2019.12.014. Epub 2020 Jan 14. Mol Ther. 2020. PMID: 31981494 Free PMC article.
432 results