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A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
Björkqvist M, Wild EJ, Thiele J, Silvestroni A, Andre R, Lahiri N, Raibon E, Lee RV, Benn CL, Soulet D, Magnusson A, Woodman B, Landles C, Pouladi MA, Hayden MR, Khalili-Shirazi A, Lowdell MW, Brundin P, Bates GP, Leavitt BR, Möller T, Tabrizi SJ. Björkqvist M, et al. Among authors: pouladi ma. J Exp Med. 2008 Aug 4;205(8):1869-77. doi: 10.1084/jem.20080178. Epub 2008 Jul 14. J Exp Med. 2008. PMID: 18625748 Free PMC article.
iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer.
Park DS, Kozaki T, Tiwari SK, Moreira M, Khalilnezhad A, Torta F, Olivié N, Thiam CH, Liani O, Silvin A, Phoo WW, Gao L, Triebl A, Tham WK, Gonçalves L, Kong WT, Raman S, Zhang XM, Dunsmore G, Dutertre CA, Lee S, Ong JM, Balachander A, Khalilnezhad S, Lum J, Duan K, Lim ZM, Tan L, Low I, Utami KH, Yeo XY, Di Tommaso S, Dupuy JW, Varga B, Karadottir RT, Madathummal MC, Bonne I, Malleret B, Binte ZY, Wei Da N, Tan Y, Wong WJ, Zhang J, Chen J, Sobota RM, Howland SW, Ng LG, Saltel F, Castel D, Grill J, Minard V, Albani S, Chan JKY, Thion MS, Jung SY, Wenk MR, Pouladi MA, Pasqualini C, Angeli V, Cexus ONF, Ginhoux F. Park DS, et al. Among authors: pouladi ma. Nature. 2023 Nov;623(7986):397-405. doi: 10.1038/s41586-023-06713-1. Epub 2023 Nov 1. Nature. 2023. PMID: 37914940
Dysregulated COMT Expression in Fragile X Syndrome.
Utami KH, Yusof NABM, Garcia-Miralles M, Skotte NH, Nama S, Sampath P, Langley SR, Pouladi MA. Utami KH, et al. Among authors: pouladi ma. Neuromolecular Med. 2023 Dec;25(4):644-649. doi: 10.1007/s12017-023-08754-1. Epub 2023 Sep 8. Neuromolecular Med. 2023. PMID: 37684514
Age-Dependent Increase in Tau Phosphorylation at Serine 396 in Huntington's Disease Prefrontal Cortex.
Petrozziello T, Huntress SS, Castillo-Torres AL, Quinn JP, Connors TR, Auger CA, Mills AN, Kim SE, Liu S, Mahmood F, Boudi A, Wu M, Sapp E, Kivisäkk P, Sunderesh SR, Pouladi MA, Arnold SE, Hyman BT, Rosas HD, DiFiglia M, Mouro Pinto R, Kegel-Gleason K, Sadri-Vakili G. Petrozziello T, et al. Among authors: pouladi ma. J Huntingtons Dis. 2023;12(3):267-281. doi: 10.3233/JHD-230588. J Huntingtons Dis. 2023. PMID: 37694372
Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage.
Kuhn A, Goldstein DR, Hodges A, Strand AD, Sengstag T, Kooperberg C, Becanovic K, Pouladi MA, Sathasivam K, Cha JH, Hannan AJ, Hayden MR, Leavitt BR, Dunnett SB, Ferrante RJ, Albin R, Shelbourne P, Delorenzi M, Augood SJ, Faull RL, Olson JM, Bates GP, Jones L, Luthi-Carter R. Kuhn A, et al. Among authors: pouladi ma. Hum Mol Genet. 2007 Aug 1;16(15):1845-61. doi: 10.1093/hmg/ddm133. Epub 2007 May 21. Hum Mol Genet. 2007. PMID: 17519223
Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease.
Graham RK, Pouladi MA, Joshi P, Lu G, Deng Y, Wu NP, Figueroa BE, Metzler M, André VM, Slow EJ, Raymond L, Friedlander R, Levine MS, Leavitt BR, Hayden MR. Graham RK, et al. Among authors: pouladi ma. J Neurosci. 2009 Feb 18;29(7):2193-204. doi: 10.1523/JNEUROSCI.5473-08.2009. J Neurosci. 2009. PMID: 19228972 Free PMC article.
Mouse models of Huntington disease: variations on a theme.
Ehrnhoefer DE, Butland SL, Pouladi MA, Hayden MR. Ehrnhoefer DE, et al. Among authors: pouladi ma. Dis Model Mech. 2009 Mar-Apr;2(3-4):123-9. doi: 10.1242/dmm.002451. Dis Model Mech. 2009. PMID: 19259385 Free PMC article.
95 results