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Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice.
Chaparala A, Poudyal D, Tashkandi H, Witalison EE, Chumanevich AA, Hofseth JL, Nguyen I, Hardy O, Pittman DL, Wyatt MD, Windust A, Murphy EA, Nagarkatti M, Nagarkatti P, Hofseth LJ. Chaparala A, et al. Among authors: poudyal d. Oncotarget. 2020 Jun 2;11(22):2026-2036. doi: 10.18632/oncotarget.27592. eCollection 2020 Jun 2. Oncotarget. 2020. PMID: 32547701 Free PMC article.
American ginseng suppresses colitis through p53-mediated apoptosis of inflammatory cells.
Jin Y, Hofseth AB, Cui X, Windust AJ, Poudyal D, Chumanevich AA, Matesic LE, Singh NP, Nagarkatti M, Nagarkatti PS, Hofseth LJ. Jin Y, et al. Among authors: poudyal d. Cancer Prev Res (Phila). 2010 Mar;3(3):339-47. doi: 10.1158/1940-6207.CAPR-09-0116. Epub 2010 Feb 23. Cancer Prev Res (Phila). 2010. PMID: 20179294 Free PMC article.
Resveratrol suppresses colitis and colon cancer associated with colitis.
Cui X, Jin Y, Hofseth AB, Pena E, Habiger J, Chumanevich A, Poudyal D, Nagarkatti M, Nagarkatti PS, Singh UP, Hofseth LJ. Cui X, et al. Among authors: poudyal d. Cancer Prev Res (Phila). 2010 Apr;3(4):549-59. doi: 10.1158/1940-6207.CAPR-09-0117. Epub 2010 Mar 23. Cancer Prev Res (Phila). 2010. PMID: 20332304 Free PMC article.
Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor.
Chumanevich AA, Causey CP, Knuckley BA, Jones JE, Poudyal D, Chumanevich AP, Davis T, Matesic LE, Thompson PR, Hofseth LJ. Chumanevich AA, et al. Among authors: poudyal d. Am J Physiol Gastrointest Liver Physiol. 2011 Jun;300(6):G929-38. doi: 10.1152/ajpgi.00435.2010. Epub 2011 Mar 17. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21415415 Free PMC article.
A hexane fraction of American ginseng suppresses mouse colitis and associated colon cancer: anti-inflammatory and proapoptotic mechanisms.
Poudyal D, Le PM, Davis T, Hofseth AB, Chumanevich A, Chumanevich AA, Wargovich MJ, Nagarkatti M, Nagarkatti PS, Windust A, Hofseth LJ. Poudyal D, et al. Cancer Prev Res (Phila). 2012 Apr;5(4):685-96. doi: 10.1158/1940-6207.CAPR-11-0421. Epub 2012 Jan 31. Cancer Prev Res (Phila). 2012. PMID: 22293630 Free PMC article.
29 results