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Specific Mutations in the Cholesterol-Binding Site of APP Alter Its Processing and Favor the Production of Shorter, Less Toxic Aβ Peptides.
Hanbouch L, Schaack B, Kasri A, Fontaine G, Gkanatsiou E, Brinkmalm G, Camporesi E, Portelius E, Blennow K, Mourier G, Gilles N, Millan MJ, Marquer C, Zetterberg H, Boussicault L, Potier MC. Hanbouch L, et al. Among authors: potier mc. Mol Neurobiol. 2022 Nov;59(11):7056-7073. doi: 10.1007/s12035-022-03025-9. Epub 2022 Sep 9. Mol Neurobiol. 2022. PMID: 36076005 Free PMC article.
Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer's disease early phenotypes.
Marquer C, Laine J, Dauphinot L, Hanbouch L, Lemercier-Neuillet C, Pierrot N, Bossers K, Le M, Corlier F, Benstaali C, Saudou F, Thinakaran G, Cartier N, Octave JN, Duyckaerts C, Potier MC. Marquer C, et al. Among authors: potier mc. Mol Neurodegener. 2014 Dec 18;9:60. doi: 10.1186/1750-1326-9-60. Mol Neurodegener. 2014. PMID: 25524049 Free PMC article.
CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease.
Djelti F, Braudeau J, Hudry E, Dhenain M, Varin J, Bièche I, Marquer C, Chali F, Ayciriex S, Auzeil N, Alves S, Langui D, Potier MC, Laprevote O, Vidaud M, Duyckaerts C, Miles R, Aubourg P, Cartier N. Djelti F, et al. Among authors: potier mc. Brain. 2015 Aug;138(Pt 8):2383-98. doi: 10.1093/brain/awv166. Epub 2015 Jul 2. Brain. 2015. PMID: 26141492
Specific Triazine Herbicides Induce Amyloid-β42 Production.
Portelius E, Durieu E, Bodin M, Cam M, Pannee J, Leuxe C, Mabondzo A, Oumata N, Galons H, Lee JY, Chang YT, Stϋber K, Koch P, Fontaine G, Potier MC, Manousopoulou A, Garbis SD, Covaci A, Van Dam D, De Deyn P, Karg F, Flajolet M, Omori C, Hata S, Suzuki T, Blennow K, Zetterberg H, Meijer L. Portelius E, et al. Among authors: potier mc. J Alzheimers Dis. 2016 Oct 18;54(4):1593-1605. doi: 10.3233/JAD-160310. J Alzheimers Dis. 2016. PMID: 27589520
Cortical amyloid accumulation is associated with alterations of structural integrity in older people with subjective memory complaints.
Teipel SJ, Cavedo E, Weschke S, Grothe MJ, Rojkova K, Fontaine G, Dauphinot L, Gonzalez-Escamilla G, Potier MC, Bertin H, Habert MO, Dubois B, Hampel H; INSIGHT-preAD study group. Teipel SJ, et al. Among authors: potier mc. Neurobiol Aging. 2017 Sep;57:143-152. doi: 10.1016/j.neurobiolaging.2017.05.016. Epub 2017 May 31. Neurobiol Aging. 2017. PMID: 28646687
320 results