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Retinoic acid promotes fibrinolysis and may regulate polyp formation.
Sakashita M, Takabayashi T, Imoto Y, Homma T, Yoshida K, Ogi K, Kimura Y, Kato A, Stevens WW, Smith SS, Welch KC, Norton JE, Suh LA, Carter RG, Hulse KE, Seshadri S, Min JY, Pothoven KL, Conley DB, Tan BK, Harris KE, Kern RC, Haruna S, Matsuwaki Y, Ochiai R, Fujieda S, Schleimer RP. Sakashita M, et al. Among authors: pothoven kl. J Allergy Clin Immunol. 2022 Nov;150(5):1114-1124.e3. doi: 10.1016/j.jaci.2022.05.021. Epub 2022 Jun 18. J Allergy Clin Immunol. 2022. PMID: 35728655
Oncostatin M promotes mucosal epithelial barrier dysfunction, and its expression is increased in patients with eosinophilic mucosal disease.
Pothoven KL, Norton JE, Hulse KE, Suh LA, Carter RG, Rocci E, Harris KE, Shintani-Smith S, Conley DB, Chandra RK, Liu MC, Kato A, Gonsalves N, Grammer LC 3rd, Peters AT, Kern RC, Bryce PJ, Tan BK, Schleimer RP. Pothoven KL, et al. J Allergy Clin Immunol. 2015 Sep;136(3):737-746.e4. doi: 10.1016/j.jaci.2015.01.043. Epub 2015 Apr 1. J Allergy Clin Immunol. 2015. PMID: 25840724 Free PMC article.
Proton pump inhibitors decrease eotaxin-3/CCL26 expression in patients with chronic rhinosinusitis with nasal polyps: Possible role of the nongastric H,K-ATPase.
Min JY, Ocampo CJ, Stevens WW, Price CPE, Thompson CF, Homma T, Huang JH, Norton JE, Suh LA, Pothoven KL, Conley DB, Welch KC, Shintani-Smith S, Peters AT, Grammer LC 3rd, Harris KE, Hulse KE, Kato A, Modyanov NN, Kern RC, Schleimer RP, Tan BK. Min JY, et al. Among authors: pothoven kl. J Allergy Clin Immunol. 2017 Jan;139(1):130-141.e11. doi: 10.1016/j.jaci.2016.07.020. Epub 2016 Oct 4. J Allergy Clin Immunol. 2017. PMID: 27717558 Free PMC article.
Neutrophils are a major source of the epithelial barrier disrupting cytokine oncostatin M in patients with mucosal airways disease.
Pothoven KL, Norton JE, Suh LA, Carter RG, Harris KE, Biyasheva A, Welch K, Shintani-Smith S, Conley DB, Liu MC, Kato A, Avila PC, Hamid Q, Grammer LC 3rd, Peters AT, Kern RC, Tan BK, Schleimer RP. Pothoven KL, et al. J Allergy Clin Immunol. 2017 Jun;139(6):1966-1978.e9. doi: 10.1016/j.jaci.2016.10.039. Epub 2016 Dec 18. J Allergy Clin Immunol. 2017. PMID: 27993536 Free PMC article.
12 results