Exploiting cross-reactivity to neutralize two different scorpion venoms with one single chain antibody fragment.
Riaño-Umbarila L, Contreras-Ferrat G, Olamendi-Portugal T, Morelos-Juárez C, Corzo G, Possani LD, Becerril B.
Riaño-Umbarila L, et al. Among authors: possani ld.
J Biol Chem. 2011 Feb 25;286(8):6143-51. doi: 10.1074/jbc.M110.189175. Epub 2010 Dec 14.
J Biol Chem. 2011.
PMID: 21156801
Free PMC article.
., Juarez-Gonzalez, V. R., Olamendi-Portugal, T., Ortiz-Leon, M., Possani, L. D., and Becerril, B. (2005) FEBS J. 272, 2591-2601) and Css2 (this work). ...Combination of these changes resulted in the scFv LR, which is capable of rescuing mice from severe envenomation by 3 …
., Juarez-Gonzalez, V. R., Olamendi-Portugal, T., Ortiz-Leon, M., Possani, L. D., and Becerril, B. (2005) FEBS J. 272, 2591-2601) and …