Pospiech H - Search Results

1

Partial Reduction in BRCA1 Gene Dose Modulates DNA Replication Stress Level and Thereby Contributes to Sensitivity or Resistance.

Classen S, Rahlf E, Jungwirth J, Albers N, Hebestreit LP, Zielinski A, Poole L, Groth M, Koch P, Liehr T, Kankel S, Cordes N, Petersen C, Rothkamm K, Pospiech H, Borgmann K. Classen S, et al. Among authors: pospiech h. Int J Mol Sci. 2022 Nov 1;23(21):13363. doi: 10.3390/ijms232113363. Int J Mol Sci. 2022. PMID: 36362151 Free PMC article.

2

Heterozygous mutations in PALB2 cause DNA replication and damage response defects.

Nikkilä J, Parplys AC, Pylkäs K, Bose M, Huo Y, Borgmann K, Rapakko K, Nieminen P, Xia B, Pospiech H, Winqvist R. Nikkilä J, et al. Among authors: pospiech h. Nat Commun. 2013;4:2578. doi: 10.1038/ncomms3578. Nat Commun. 2013. PMID: 24153426 Free PMC article.

3

High levels of RAD51 perturb DNA replication elongation and cause unscheduled origin firing due to impaired CHK1 activation.

Parplys AC, Seelbach JI, Becker S, Behr M, Wrona A, Jend C, Mansour WY, Joosse SA, Stuerzbecher HW, Pospiech H, Petersen C, Dikomey E, Borgmann K. Parplys AC, et al. Among authors: pospiech h. Cell Cycle. 2015;14(19):3190-202. doi: 10.1080/15384101.2015.1055996. Cell Cycle. 2015. PMID: 26317153 Free PMC article.

4

Heterozygous PALB2 c.1592delT mutation channels DNA double-strand break repair into error-prone pathways in breast cancer patients.

Obermeier K, Sachsenweger J, Friedl TW, Pospiech H, Winqvist R, Wiesmüller L. Obermeier K, et al. Among authors: pospiech h. Oncogene. 2016 Jul 21;35(29):3796-806. doi: 10.1038/onc.2015.448. Epub 2015 Dec 7. Oncogene. 2016. PMID: 26640152 Free PMC article.

5

Cdc45 is limiting for replication initiation in humans.

Köhler C, Koalick D, Fabricius A, Parplys AC, Borgmann K, Pospiech H, Grosse F. Köhler C, et al. Among authors: pospiech h. Cell Cycle. 2016;15(7):974-85. doi: 10.1080/15384101.2016.1152424. Cell Cycle. 2016. PMID: 26919204 Free PMC article.

6

S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci.

Foertsch F, Szambowska A, Weise A, Zielinski A, Schlott B, Kraft F, Mrasek K, Borgmann K, Pospiech H, Grosse F, Melle C. Foertsch F, et al. Among authors: pospiech h. Cell Cycle. 2016 Oct 17;15(20):2766-79. doi: 10.1080/15384101.2016.1220457. Epub 2016 Aug 11. Cell Cycle. 2016. PMID: 27590262 Free PMC article.

7

TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress.

Pai GM, Zielinski A, Koalick D, Ludwig K, Wang ZQ, Borgmann K, Pospiech H, Rubio I. Pai GM, et al. Among authors: pospiech h. Oncotarget. 2016 Dec 20;7(51):85365-85380. doi: 10.18632/oncotarget.13378. Oncotarget. 2016. PMID: 27863419 Free PMC article.

8

The ATR-Activation Domain of TopBP1 Is Required for the Suppression of Origin Firing during the S Phase.

Sokka M, Koalick D, Hemmerich P, Syväoja JE, Pospiech H. Sokka M, et al. Among authors: pospiech h. Int J Mol Sci. 2018 Aug 13;19(8):2376. doi: 10.3390/ijms19082376. Int J Mol Sci. 2018. PMID: 30104465 Free PMC article.

9

BRCA1 mislocalization leads to aberrant DNA damage response in heterozygous ABRAXAS1 mutation carrier cells.

Bose M, Sachsenweger J, Laurila N, Parplys AC, Willmann J, Jungwirth J, Groth M, Rapakko K, Nieminen P, Friedl TWP, Heiserich L, Meyer F, Tuppurainen H, Peltoketo H, Nevanlinna H, Pylkäs K, Borgmann K, Wiesmüller L, Winqvist R, Pospiech H. Bose M, et al. Among authors: pospiech h. Hum Mol Genet. 2019 Dec 15;28(24):4148-4160. doi: 10.1093/hmg/ddz252. Hum Mol Genet. 2019. PMID: 31630195

10

BRCT domain-containing protein TopBP1 functions in DNA replication and damage response.

Mäkiniemi M, Hillukkala T, Tuusa J, Reini K, Vaara M, Huang D, Pospiech H, Majuri I, Westerling T, Mäkelä TP, Syväoja JE. Mäkiniemi M, et al. Among authors: pospiech h. J Biol Chem. 2001 Aug 10;276(32):30399-406. doi: 10.1074/jbc.M102245200. Epub 2001 Jun 6. J Biol Chem. 2001. PMID: 11395493 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

51 results

Search Page