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Iron overload and immunity.
Porto G, De Sousa M. Porto G, et al. World J Gastroenterol. 2007 Sep 21;13(35):4707-15. doi: 10.3748/wjg.v13.i35.4707. World J Gastroenterol. 2007. PMID: 17729392 Free PMC article. Review.
Lymphocyte gene expression signatures from patients and mouse models of hereditary hemochromatosis reveal a function of HFE as a negative regulator of CD8+ T-lymphocyte activation and differentiation in vivo.
Costa M, Cruz E, Oliveira S, Benes V, Ivacevic T, Silva MJ, Vieira I, Dias F, Fonseca S, Gonçalves M, Lima M, Leitão C, Muckenthaler MU, Pinto J, Porto G. Costa M, et al. Among authors: porto g. PLoS One. 2015 Apr 16;10(4):e0124246. doi: 10.1371/journal.pone.0124246. eCollection 2015. PLoS One. 2015. PMID: 25880808 Free PMC article.
Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.
Pasricha SR, Lim PJ, Duarte TL, Casu C, Oosterhuis D, Mleczko-Sanecka K, Suciu M, Da Silva AR, Al-Hourani K, Arezes J, McHugh K, Gooding S, Frost JN, Wray K, Santos A, Porto G, Repapi E, Gray N, Draper SJ, Ashley N, Soilleux E, Olinga P, Muckenthaler MU, Hughes JR, Rivella S, Milne TA, Armitage AE, Drakesmith H. Pasricha SR, et al. Among authors: porto g. Nat Commun. 2017 Sep 1;8(1):403. doi: 10.1038/s41467-017-00500-z. Nat Commun. 2017. PMID: 28864822 Free PMC article.
Loss of erythroblasts in acute myeloid leukemia causes iron redistribution with clinical implications.
Lopes M, Duarte TL, Teles MJ, Mosteo L, Chacim S, Aguiar E, Pereira-Reis J, Oliveira M, Silva AMN, Gonçalves N, Martins G, Kong IY, Zethoven M, Vervoort S, Martins S, Quintela M, Hawkins ED, Trigo F, Guimarães JT, Mariz JM, Porto G, Duarte D. Lopes M, et al. Among authors: porto g. Blood Adv. 2021 Aug 24;5(16):3102-3112. doi: 10.1182/bloodadvances.2021004373. Blood Adv. 2021. PMID: 34402883 Free PMC article.
333 results