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The Small-Compound Inhibitor K22 Displays Broad Antiviral Activity against Different Members of the Family Flaviviridae and Offers Potential as a Panviral Inhibitor.
García-Nicolás O, V'kovski P, Vielle NJ, Ebert N, Züst R, Portmann J, Stalder H, Gaschen V, Vieyres G, Stoffel M, Schweizer M, Summerfield A, Engler O, Pietschmann T, Todt D, Alves MP, Thiel V, Pfaender S. García-Nicolás O, et al. Among authors: portmann j. Antimicrob Agents Chemother. 2018 Oct 24;62(11):e01206-18. doi: 10.1128/AAC.01206-18. Print 2018 Nov. Antimicrob Agents Chemother. 2018. PMID: 30181371 Free PMC article.
Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform.
Thi Nhu Thao T, Labroussaa F, Ebert N, V'kovski P, Stalder H, Portmann J, Kelly J, Steiner S, Holwerda M, Kratzel A, Gultom M, Schmied K, Laloli L, Hüsser L, Wider M, Pfaender S, Hirt D, Cippà V, Crespo-Pomar S, Schröder S, Muth D, Niemeyer D, Corman VM, Müller MA, Drosten C, Dijkman R, Jores J, Thiel V. Thi Nhu Thao T, et al. Among authors: portmann j. Nature. 2020 Jun;582(7813):561-565. doi: 10.1038/s41586-020-2294-9. Epub 2020 May 4. Nature. 2020. PMID: 32365353
SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility.
Zhou B, Thao TTN, Hoffmann D, Taddeo A, Ebert N, Labroussaa F, Pohlmann A, King J, Portmann J, Halwe NJ, Ulrich L, Trüeb BS, Kelly JN, Fan X, Hoffmann B, Steiner S, Wang L, Thomann L, Lin X, Stalder H, Pozzi B, de Brot S, Jiang N, Cui D, Hossain J, Wilson M, Keller M, Stark TJ, Barnes JR, Dijkman R, Jores J, Benarafa C, Wentworth DE, Thiel V, Beer M. Zhou B, et al. Among authors: portmann j. bioRxiv [Preprint]. 2020 Oct 27:2020.10.27.357558. doi: 10.1101/2020.10.27.357558. bioRxiv. 2020. PMID: 33140052 Free PMC article. Updated. Preprint.
SARS-CoV-2 spike D614G change enhances replication and transmission.
Zhou B, Thao TTN, Hoffmann D, Taddeo A, Ebert N, Labroussaa F, Pohlmann A, King J, Steiner S, Kelly JN, Portmann J, Halwe NJ, Ulrich L, Trüeb BS, Fan X, Hoffmann B, Wang L, Thomann L, Lin X, Stalder H, Pozzi B, de Brot S, Jiang N, Cui D, Hossain J, Wilson MM, Keller MW, Stark TJ, Barnes JR, Dijkman R, Jores J, Benarafa C, Wentworth DE, Thiel V, Beer M. Zhou B, et al. Among authors: portmann j. Nature. 2021 Apr;592(7852):122-127. doi: 10.1038/s41586-021-03361-1. Epub 2021 Feb 26. Nature. 2021. PMID: 33636719
Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium.
V'kovski P, Gultom M, Kelly JN, Steiner S, Russeil J, Mangeat B, Cora E, Pezoldt J, Holwerda M, Kratzel A, Laloli L, Wider M, Portmann J, Tran T, Ebert N, Stalder H, Hartmann R, Gardeux V, Alpern D, Deplancke B, Thiel V, Dijkman R. V'kovski P, et al. Among authors: portmann j. PLoS Biol. 2021 Mar 29;19(3):e3001158. doi: 10.1371/journal.pbio.3001158. eCollection 2021 Mar. PLoS Biol. 2021. PMID: 33780434 Free PMC article.
Susceptibility of Well-Differentiated Airway Epithelial Cell Cultures from Domestic and Wild Animals to Severe Acute Respiratory Syndrome Coronavirus 2.
Gultom M, Licheri M, Laloli L, Wider M, Strässle M, V'kovski P, Steiner S, Kratzel A, Thao TTN, Probst L, Stalder H, Portmann J, Holwerda M, Ebert N, Stokar-Regenscheit N, Gurtner C, Zanolari P, Posthaus H, Schuller S, Vicente-Santos A, Moreira-Soto A, Corrales-Aguilar E, Ruggli N, Tekes G, von Messling V, Sawatsky B, Thiel V, Dijkman R. Gultom M, et al. Among authors: portmann j. Emerg Infect Dis. 2021 Jul;27(7):1811-1820. doi: 10.3201/eid2707.204660. Emerg Infect Dis. 2021. PMID: 34152956 Free PMC article.
A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets.
Kratzel A, Kelly JN, V'kovski P, Portmann J, Brüggemann Y, Todt D, Ebert N, Shrestha N, Plattet P, Staab-Weijnitz CA, von Brunn A, Steinmann E, Dijkman R, Zimmer G, Pfaender S, Thiel V. Kratzel A, et al. Among authors: portmann j. PLoS Biol. 2021 Dec 28;19(12):e3001490. doi: 10.1371/journal.pbio.3001490. eCollection 2021 Dec. PLoS Biol. 2021. PMID: 34962926 Free PMC article.
60 results