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O-GlcNAcylated p53 in the liver modulates hepatic glucose production.
Gonzalez-Rellan MJ, Fondevila MF, Fernandez U, Rodríguez A, Varela-Rey M, Veyrat-Durebex C, Seoane S, Bernardo G, Lopitz-Otsoa F, Fernández-Ramos D, Bilbao J, Iglesias C, Novoa E, Ameneiro C, Senra A, Beiroa D, Cuñarro J, Dp Chantada-Vazquez M, Garcia-Vence M, Bravo SB, Da Silva Lima N, Porteiro B, Carneiro C, Vidal A, Tovar S, Müller TD, Ferno J, Guallar D, Fidalgo M, Sabio G, Herzig S, Yang WH, Cho JW, Martinez-Chantar ML, Perez-Fernandez R, López M, Dieguez C, Mato JM, Millet O, Coppari R, Woodhoo A, Fruhbeck G, Nogueiras R. Gonzalez-Rellan MJ, et al. Among authors: porteiro b. Nat Commun. 2021 Aug 20;12(1):5068. doi: 10.1038/s41467-021-25390-0. Nat Commun. 2021. PMID: 34417460 Free PMC article.
Hepatic p63 regulates steatosis via IKKβ/ER stress.
Porteiro B, Fondevila MF, Delgado TC, Iglesias C, Imbernon M, Iruzubieta P, Crespo J, Zabala-Letona A, Fernø J, González-Terán B, Matesanz N, Hernández-Cosido L, Marcos M, Tovar S, Vidal A, Sánchez-Ceinos J, Malagon MM, Pombo C, Zalvide J, Carracedo A, Buque X, Dieguez C, Sabio G, López M, Aspichueta P, Martínez-Chantar ML, Nogueiras R. Porteiro B, et al. Nat Commun. 2017 May 8;8:15111. doi: 10.1038/ncomms15111. Nat Commun. 2017. PMID: 28480888 Free PMC article.
Ghrelin requires p53 to stimulate lipid storage in fat and liver.
Porteiro B, Díaz-Ruíz A, Martínez G, Senra A, Vidal A, Serrano M, Gualillo O, López M, Malagón MM, Diéguez C, Nogueiras R. Porteiro B, et al. Endocrinology. 2013 Oct;154(10):3671-9. doi: 10.1210/en.2013-1176. Epub 2013 Jul 5. Endocrinology. 2013. PMID: 23832961
Pharmacological and Genetic Manipulation of p53 in Brown Fat at Adult But Not Embryonic Stages Regulates Thermogenesis and Body Weight in Male Mice.
Al-Massadi O, Porteiro B, Kuhlow D, Köhler M, Gonzalez-Rellan MJ, Garcia-Lavandeira M, Díaz-Rodríguez E, Quiñones M, Senra A, Alvarez CV, López M, Diéguez C, Schulz TJ, Nogueiras R. Al-Massadi O, et al. Among authors: porteiro b. Endocrinology. 2016 Jul;157(7):2735-49. doi: 10.1210/en.2016-1209. Epub 2016 May 16. Endocrinology. 2016. PMID: 27183316
The MST3/STK24 kinase mediates impaired fasting blood glucose after a high-fat diet.
Iglesias C, Floridia E, Sartages M, Porteiro B, Fraile M, Guerrero A, Santos D, Cuñarro J, Tovar S, Nogueiras R, Pombo CM, Zalvide J. Iglesias C, et al. Among authors: porteiro b. Diabetologia. 2017 Dec;60(12):2453-2462. doi: 10.1007/s00125-017-4433-x. Epub 2017 Sep 27. Diabetologia. 2017. PMID: 28956081
The L-α-Lysophosphatidylinositol/G Protein-Coupled Receptor 55 System Induces the Development of Nonalcoholic Steatosis and Steatohepatitis.
Fondevila MF, Fernandez U, Gonzalez-Rellan MJ, Da Silva Lima N, Buque X, Gonzalez-Rodriguez A, Alonso C, Iruarrizaga-Lejarreta M, Delgado TC, Varela-Rey M, Senra A, Garcia-Outeiral V, Novoa E, Iglesias C, Porteiro B, Beiroa D, Folgueira C, Tojo M, Torres JL, Hernández-Cosido L, Blanco Ó, Arab JP, Barrera F, Guallar D, Fidalgo M, López M, Dieguez C, Marcos M, Martinez-Chantar ML, Arrese M, Garcia-Monzon C, Mato JM, Aspichueta P, Nogueiras R. Fondevila MF, et al. Among authors: porteiro b. Hepatology. 2021 Feb;73(2):606-624. doi: 10.1002/hep.31290. Epub 2020 Nov 13. Hepatology. 2021. PMID: 32329085 Free PMC article.
31 results