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Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis.
Grigoryan A, Zacharaki D, Balhuizen A, Côme CR, Garcia AG, Hidalgo Gil D, Frank AK, Aaltonen K, Mañas A, Esfandyari J, Kjellman P, Englund E, Rodriguez C, Sime W, Massoumi R, Kalantari N, Prithiviraj S, Li Y, Dupard SJ, Isaksson H, Madsen CD, Porse BT, Bexell D, Bourgine PE. Grigoryan A, et al. Among authors: porse bt. Sci Transl Med. 2022 Oct 12;14(666):eabm6391. doi: 10.1126/scitranslmed.abm6391. Epub 2022 Oct 12. Sci Transl Med. 2022. PMID: 36223446
C/EBPα is required for long-term self-renewal and lineage priming of hematopoietic stem cells and for the maintenance of epigenetic configurations in multipotent progenitors.
Hasemann MS, Lauridsen FK, Waage J, Jakobsen JS, Frank AK, Schuster MB, Rapin N, Bagger FO, Hoppe PS, Schroeder T, Porse BT. Hasemann MS, et al. Among authors: porse bt. PLoS Genet. 2014 Jan;10(1):e1004079. doi: 10.1371/journal.pgen.1004079. Epub 2014 Jan 9. PLoS Genet. 2014. PMID: 24415956 Free PMC article.
120 results