Porru M - Search Results

1

FGFR2 fusion proteins drive oncogenic transformation of mouse liver organoids towards cholangiocarcinoma.

Cristinziano G, Porru M, Lamberti D, Buglioni S, Rollo F, Amoreo CA, Manni I, Giannarelli D, Cristofoletti C, Russo G, Borad MJ, Grazi GL, Diodoro MG, Giordano S, Sacconi A, Forcato M, Anastasi S, Leonetti C, Segatto O. Cristinziano G, et al. Among authors: porru m. J Hepatol. 2021 Aug;75(2):351-362. doi: 10.1016/j.jhep.2021.02.032. Epub 2021 Mar 17. J Hepatol. 2021. PMID: 33741397

2

Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway.

Rizzo A, Salvati E, Porru M, D'Angelo C, Stevens MF, D'Incalci M, Leonetti C, Gilson E, Zupi G, Biroccio A. Rizzo A, et al. Among authors: porru m. Nucleic Acids Res. 2009 Sep;37(16):5353-64. doi: 10.1093/nar/gkp582. Epub 2009 Jul 13. Nucleic Acids Res. 2009. PMID: 19596811 Free PMC article.

3

PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy.

Salvati E, Scarsella M, Porru M, Rizzo A, Iachettini S, Tentori L, Graziani G, D'Incalci M, Stevens MF, Orlandi A, Passeri D, Gilson E, Zupi G, Leonetti C, Biroccio A. Salvati E, et al. Among authors: porru m. Oncogene. 2010 Nov 25;29(47):6280-93. doi: 10.1038/onc.2010.344. Epub 2010 Aug 30. Oncogene. 2010. PMID: 20802516

4

Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo.

Nardinocchi L, Pantisano V, Puca R, Porru M, Aiello A, Grasselli A, Leonetti C, Safran M, Rechavi G, Givol D, Farsetti A, D'Orazi G. Nardinocchi L, et al. Among authors: porru m. PLoS One. 2010 Dec 13;5(12):e15048. doi: 10.1371/journal.pone.0015048. PLoS One. 2010. PMID: 21179202 Free PMC article.

5

DNA damage persistence as determinant of tumor sensitivity to the combination of Topo I inhibitors and telomere-targeting agents.

Biroccio A, Porru M, Rizzo A, Salvati E, D'Angelo C, Orlandi A, Passeri D, Franceschin M, Stevens MF, Gilson E, Beretta G, Zupi G, Pisano C, Zunino F, Leonetti C. Biroccio A, et al. Among authors: porru m. Clin Cancer Res. 2011 Apr 15;17(8):2227-36. doi: 10.1158/1078-0432.CCR-10-3033. Epub 2011 Feb 25. Clin Cancer Res. 2011. PMID: 21355072

6

Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs.

Puca R, Nardinocchi L, Porru M, Simon AJ, Rechavi G, Leonetti C, Givol D, D'Orazi G. Puca R, et al. Among authors: porru m. Cell Cycle. 2011 May 15;10(10):1679-89. doi: 10.4161/cc.10.10.15642. Epub 2011 May 15. Cell Cycle. 2011. PMID: 21508668

7

Evaluation of the in vitro and in vivo antiangiogenic effects of denosumab and zoledronic acid.

Misso G, Porru M, Stoppacciaro A, Castellano M, De Cicco F, Leonetti C, Santini D, Caraglia M. Misso G, et al. Among authors: porru m. Cancer Biol Ther. 2012 Dec;13(14):1491-500. doi: 10.4161/cbt.22274. Epub 2012 Sep 18. Cancer Biol Ther. 2012. PMID: 22990205 Free PMC article.

8

Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.

Salvati E, Zizza P, Rizzo A, Iachettini S, Cingolani C, D'Angelo C, Porru M, Randazzo A, Pagano B, Novellino E, Pisanu ME, Stoppacciaro A, Spinella F, Bagnato A, Gilson E, Leonetti C, Biroccio A. Salvati E, et al. Among authors: porru m. Nucleic Acids Res. 2014 Mar;42(5):2945-57. doi: 10.1093/nar/gkt1289. Epub 2013 Dec 11. Nucleic Acids Res. 2014. PMID: 24335081 Free PMC article.

9

Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities.

Rizzo A, Iachettini S, Zizza P, Cingolani C, Porru M, Artuso S, Stevens M, Hummersone M, Biroccio A, Salvati E, Leonetti C. Rizzo A, et al. Among authors: porru m. J Exp Clin Cancer Res. 2014 Oct 6;33(1):81. doi: 10.1186/s13046-014-0081-x. J Exp Clin Cancer Res. 2014. PMID: 25288403 Free PMC article.

10

Medical treatment of orthotopic glioblastoma with transferrin-conjugated nanoparticles encapsulating zoledronic acid.

Porru M, Zappavigna S, Salzano G, Luce A, Stoppacciaro A, Balestrieri ML, Artuso S, Lusa S, De Rosa G, Leonetti C, Caraglia M. Porru M, et al. Oncotarget. 2014 Nov 15;5(21):10446-59. doi: 10.18632/oncotarget.2182. Oncotarget. 2014. PMID: 25431953 Free PMC article.

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