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Inhibition of NFAT promotes loss of tissue resident uterine natural killer cells and attendant pregnancy complications in humans.
Asiimwe R, Knott B, Greene ME, Wright E, Bell M, Epstein D, Yates SD, Cheung MD, Gonzalez MV, Fry S, Boydston E, Clevenger S, Locke JE, George JF, Burney R, Arora N, Duncan VE, Richter HE, Gunn D, Freud AG, Little SC, Porrett PM. Asiimwe R, et al. Among authors: porrett pm. bioRxiv [Preprint]. 2024 Mar 12:2024.03.07.583906. doi: 10.1101/2024.03.07.583906. bioRxiv. 2024. PMID: 38559147 Free PMC article. Preprint.
B cell and antibody targeting of transplant alloantigen epitopes is supported by both self and allo-recognition.
Killian JT, King RG, Kizziah JL, Fucile CF, Diaz-Avalos R, Qiu S, Silva-Sanchez A, Mousseau BJ, Macon KJ, Callahan AR, Yang G, Hossain ME, Akther J, Houp JA, Rosenblum FD, Porrett PM, Ong SC, Kumar V, Saphire EO, Kearney JF, Randall TD, Rosenberg AF, Green TJ, Lund FE. Killian JT, et al. Among authors: porrett pm. bioRxiv [Preprint]. 2023 Jun 24:2023.03.31.534734. doi: 10.1101/2023.03.31.534734. bioRxiv. 2023. PMID: 37034637 Free PMC article. Preprint.
Spatiotemporal immune atlas of a clinical-grade gene-edited pig-to-human kidney xenotransplant.
Cheung MD, Asiimwe R, Erman EN, Fucile CF, Liu S, Sun CW, Hanumanthu VS, Pal HC, Wright ED, Ghajar-Rahimi G, Epstein D, Orandi BJ, Kumar V, Anderson DJ, Greene ME, Bell M, Yates S, Moore KH, LaFontaine J, Killian JT Jr, Baker G, Perry J, Khan Z, Reed R, Little SC, Rosenberg AF, George JF, Locke JE, Porrett PM. Cheung MD, et al. Among authors: porrett pm. Nat Commun. 2024 Apr 11;15(1):3140. doi: 10.1038/s41467-024-47454-7. Nat Commun. 2024. PMID: 38605083 Free PMC article.
Physiologic homeostasis after pig-to-human kidney xenotransplantation.
Judd E, Kumar V, Porrett PM, Hyndman KA, Anderson DJ, Jones-Carr ME, Shunk A, Epstein DR, Fatima H, Katsurada A, Satou R, Navar LG, Locke JE. Judd E, et al. Among authors: porrett pm. Kidney Int. 2024 May;105(5):971-979. doi: 10.1016/j.kint.2024.01.016. Epub 2024 Jan 28. Kidney Int. 2024. PMID: 38290599 Free article.
How mothers tolerate their children.
Porrett PM. Porrett PM. Science. 2023 Sep 22;381(6664):1286. doi: 10.1126/science.adk1218. Epub 2023 Sep 21. Science. 2023. PMID: 37733842
58 results