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Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread.
Nucleic Acids Res. 2022 Jan 11;50(1):333-349. doi: 10.1093/nar/gkab1248.
Nucleic Acids Res. 2022.
PMID: 34928377
Free PMC article.
Inhibition of SARS-CoV-2 replication in the lung with siRNA/VIPER polyplexes.
Baldassi D, Ambike S, Feuerherd M, Cheng CC, Peeler DJ, Feldmann DP, Porras-Gonzalez DL, Wei X, Keller LA, Kneidinger N, Stoleriu MG, Popp A, Burgstaller G, Pun SH, Michler T, Merkel OM.
Baldassi D, et al. Among authors: porras gonzalez dl.
J Control Release. 2022 May;345:661-674. doi: 10.1016/j.jconrel.2022.03.051. Epub 2022 Mar 29.
J Control Release. 2022.
PMID: 35364120
Free PMC article.
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Spray drying siRNA-lipid nanoparticles for dry powder pulmonary delivery.
Zimmermann CM, Baldassi D, Chan K, Adams NBP, Neumann A, Porras-Gonzalez DL, Wei X, Kneidinger N, Stoleriu MG, Burgstaller G, Witzigmann D, Luciani P, Merkel OM.
Zimmermann CM, et al. Among authors: porras gonzalez dl.
J Control Release. 2022 Nov;351:137-150. doi: 10.1016/j.jconrel.2022.09.021. Epub 2022 Sep 22.
J Control Release. 2022.
PMID: 36126785
Free PMC article.
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Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis.
Lang NJ, Gote-Schniering J, Porras-Gonzalez D, Yang L, De Sadeleer LJ, Jentzsch RC, Shitov VA, Zhou S, Ansari M, Agami A, Mayr CH, Hooshiar Kashani B, Chen Y, Heumos L, Pestoni JC, Molnar ES, Geeraerts E, Anquetil V, Saniere L, Wögrath M, Gerckens M, Lehmann M, Yildirim AÖ, Hatz R, Kneidinger N, Behr J, Wuyts WA, Stoleriu MG, Luecken MD, Theis FJ, Burgstaller G, Schiller HB.
Lang NJ, et al. Among authors: porras gonzalez d.
Sci Transl Med. 2023 Dec 6;15(725):eadh0908. doi: 10.1126/scitranslmed.adh0908. Epub 2023 Dec 6.
Sci Transl Med. 2023.
PMID: 38055803
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Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts.
Mayr CH, Sengupta A, Asgharpour S, Ansari M, Pestoni JC, Ogar P, Angelidis I, Liontos A, Rodriguez-Castillo JA, Lang NJ, Strunz M, Porras-Gonzalez D, Gerckens M, De Sadeleer LJ, Oehrle B, Viteri-Alvarez V, Fernandez IE, Tallquist M, Irmler M, Beckers J, Eickelberg O, Stoleriu GM, Behr J, Kneidinger N, Wuyts WA, Wasnick RM, Yildirim AÖ, Ahlbrecht K, Morty RE, Samakovlis C, Theis FJ, Burgstaller G, Schiller HB.
Mayr CH, et al. Among authors: porras gonzalez d.
Eur Respir J. 2024 Feb 8;63(2):2301326. doi: 10.1183/13993003.01326-2023. Print 2024 Feb.
Eur Respir J. 2024.
PMID: 38212077
Free PMC article.
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Sex Hormones Regulate SHANK Expression.
Berkel S, Eltokhi A, Fröhlich H, Porras-Gonzalez D, Rafiullah R, Sprengel R, Rappold GA.
Berkel S, et al. Among authors: porras gonzalez d.
Front Mol Neurosci. 2018 Sep 25;11:337. doi: 10.3389/fnmol.2018.00337. eCollection 2018.
Front Mol Neurosci. 2018.
PMID: 30319350
Free PMC article.
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