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COR758, a negative allosteric modulator of GABAB receptors.
Porcu A, Mostallino R, Serra V, Melis M, Sogos V, Beggiato S, Ferraro L, Manetti F, Gianibbi B, Bettler B, Corelli F, Mugnaini C, Castelli MP. Porcu A, et al. Neuropharmacology. 2021 May 15;189:108537. doi: 10.1016/j.neuropharm.2021.108537. Epub 2021 Mar 30. Neuropharmacology. 2021. PMID: 33798546
Synthesis and pharmacological characterization of 2-(acylamino)thiophene derivatives as metabolically stable, orally effective, positive allosteric modulators of the GABAB receptor.
Mugnaini C, Pedani V, Casu A, Lobina C, Casti A, Maccioni P, Porcu A, Giunta D, Lamponi S, Solinas M, Dragoni S, Valoti M, Colombo G, Castelli MP, Gessa GL, Corelli F. Mugnaini C, et al. Among authors: porcu a. J Med Chem. 2013 May 9;56(9):3620-35. doi: 10.1021/jm400144w. Epub 2013 Apr 18. J Med Chem. 2013. PMID: 23544432
Native CB1 receptor affinity, intrinsic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids: BB-22, 5F-PB-22, 5F-AKB-48 and STS-135.
De Luca MA, Castelli MP, Loi B, Porcu A, Martorelli M, Miliano C, Kellett K, Davidson C, Stair JL, Schifano F, Di Chiara G. De Luca MA, et al. Among authors: porcu a. Neuropharmacology. 2016 Jun;105:630-638. doi: 10.1016/j.neuropharm.2015.11.017. Epub 2015 Dec 11. Neuropharmacology. 2016. PMID: 26686391
The new compound GET73, N-[(4-trifluoromethyl)benzyl]4-methoxybutyramide, Regulates hippocampal Aminoacidergic transmission possibly via an allosteric modulation of mGlu5 receptor. Behavioural evidence of its "anti-alcohol" and anxiolytic properties.
Ferraro L, Loche A, Beggiato S, Tomasini MC, Antonelli T, Colombo G, Lobina C, Carai MA, Porcu A, Castelli MP, Clerici F, Borelli AC, Cacciaglia R, Tanganelli S. Ferraro L, et al. Among authors: porcu a. Curr Med Chem. 2013;20(27):3339-57. doi: 10.2174/09298673113209990167. Curr Med Chem. 2013. PMID: 23862615 Review.
Cognition in multiple sclerosis: Between cognitive reserve and brain volume.
Fenu G, Lorefice L, Arru M, Sechi V, Loi L, Contu F, Cabras F, Coghe G, Frau J, Fronza M, Sbrescia G, Lai V, Boi M, Mallus S, Murru S, Porcu A, Barracciu MA, Marrosu MG, Cocco E. Fenu G, et al. Among authors: porcu a. J Neurol Sci. 2018 Mar 15;386:19-22. doi: 10.1016/j.jns.2018.01.011. Epub 2018 Jan 10. J Neurol Sci. 2018. PMID: 29406960
A metabolomics comparison between sheep's and goat's milk.
Caboni P, Murgia A, Porcu A, Manis C, Ibba I, Contu M, Scano P. Caboni P, et al. Among authors: porcu a. Food Res Int. 2019 May;119:869-875. doi: 10.1016/j.foodres.2018.10.071. Epub 2018 Oct 26. Food Res Int. 2019. PMID: 30884727
Five-year recurrence/survival after pancreatoduodenectomy for pancreatic adenocarcinoma: does pre-existing diabetes matter? Results from the Recurrence After Whipple's (RAW) study.
Rajagopalan A, Aroori S, Russell TB, Labib PL, Ausania F, Pando E, Roberts KJ, Kausar A, Mavroeidis VK, Marangoni G, Thomasset SC, Frampton AE, Lykoudis P, Maglione M, Alhaboob N, Bari H, Smith AM, Spalding D, Srinivasan P, Davidson BR, Bhogal RH, Dominguez I, Thakkar R, Gomez D, Silva MA, Lapolla P, Mingoli A, Porcu A, Shah NS, Hamady ZZR, Al-Sarrieh B, Serrablo A, Croagh D; RAW Study Collaborators. Rajagopalan A, et al. Among authors: porcu a. HPB (Oxford). 2024 Apr 26:S1365-182X(24)01276-0. doi: 10.1016/j.hpb.2024.04.010. Online ahead of print. HPB (Oxford). 2024. PMID: 38755085
235 results