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HIV-1 Tat protein directly induces mitochondrial membrane permeabilization and inactivates cytochrome c oxidase.
Lecoeur H, Borgne-Sanchez A, Chaloin O, El-Khoury R, Brabant M, Langonné A, Porceddu M, Brière JJ, Buron N, Rebouillat D, Péchoux C, Deniaud A, Brenner C, Briand JP, Muller S, Rustin P, Jacotot E. Lecoeur H, et al. Among authors: porceddu m. Cell Death Dis. 2012 Mar 15;3(3):e282. doi: 10.1038/cddis.2012.21. Cell Death Dis. 2012. PMID: 22419111 Free PMC article.
A flavivirus protein M-derived peptide directly permeabilizes mitochondrial membranes, triggers cell death and reduces human tumor growth in nude mice.
Brabant M, Baux L, Casimir R, Briand JP, Chaloin O, Porceddu M, Buron N, Chauvier D, Lassalle M, Lecoeur H, Langonné A, Dupont S, Déas O, Brenner C, Rebouillat D, Muller S, Borgne-Sanchez A, Jacotot E. Brabant M, et al. Among authors: porceddu m. Apoptosis. 2009 Oct;14(10):1190-203. doi: 10.1007/s10495-009-0394-y. Apoptosis. 2009. PMID: 19693674
Aftins increase amyloid-β42, lower amyloid-β38, and do not alter amyloid-β40 extracellular production in vitro: toward a chemical model of Alzheimer's disease?
Hochard A, Oumata N, Bettayeb K, Gloulou O, Fant X, Durieu E, Buron N, Porceddu M, Borgne-Sanchez A, Galons H, Flajolet M, Meijer L. Hochard A, et al. Among authors: porceddu m. J Alzheimers Dis. 2013;35(1):107-20. doi: 10.3233/JAD-121777. J Alzheimers Dis. 2013. PMID: 23364140 Free PMC article.
88 results