Porcù E - Search Results

1

Discovery and optimization of a series of 2-aryl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazoles as novel anticancer agents.

Romagnoli R, Baraldi PG, Salvador MK, Preti D, Aghazadeh Tabrizi M, Brancale A, Fu XH, Li J, Zhang SZ, Hamel E, Bortolozzi R, Porcù E, Basso G, Viola G. Romagnoli R, et al. Among authors: porcu e. J Med Chem. 2012 Jun 14;55(11):5433-45. doi: 10.1021/jm300388h. Epub 2012 May 21. J Med Chem. 2012. PMID: 22578111 Free PMC article.

2

Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles.

Romagnoli R, Baraldi PG, Salvador MK, Prencipe F, Bertolasi V, Cancellieri M, Brancale A, Hamel E, Castagliuolo I, Consolaro F, Porcù E, Basso G, Viola G. Romagnoli R, et al. Among authors: porcu e. J Med Chem. 2014 Aug 14;57(15):6795-808. doi: 10.1021/jm5008193. Epub 2014 Jul 28. J Med Chem. 2014. PMID: 25025853 Free PMC article.

3

Recent advances in vascular disrupting agents in cancer therapy.

Porcù E, Bortolozzi R, Basso G, Viola G. Porcù E, et al. Future Med Chem. 2014 Sep;6(13):1485-98. doi: 10.4155/fmc.14.104. Future Med Chem. 2014. PMID: 25365233 Review.

4

Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.

Romagnoli R, Baraldi PG, Salvador MK, Prencipe F, Lopez-Cara C, Schiaffino Ortega S, Brancale A, Hamel E, Castagliuolo I, Mitola S, Ronca R, Bortolozzi R, Porcù E, Basso G, Viola G. Romagnoli R, et al. Among authors: porcu e. J Med Chem. 2015 Apr 9;58(7):3209-22. doi: 10.1021/acs.jmedchem.5b00155. Epub 2015 Mar 26. J Med Chem. 2015. PMID: 25785605 Free PMC article.

5

Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents.

Romagnoli R, Baraldi PG, Prencipe F, Oliva P, Baraldi S, Salvador MK, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Ronca R, Bortolozzi R, Mariotto E, Porcù E, Basso G, Viola G. Romagnoli R, et al. Among authors: porcu e. Sci Rep. 2017 Apr 13;7:46356. doi: 10.1038/srep46356. Sci Rep. 2017. PMID: 28406191 Free PMC article.

6

TR-644 a novel potent tubulin binding agent induces impairment of endothelial cells function and inhibits angiogenesis.

Porcù E, Viola G, Bortolozzi R, Persano L, Mitola S, Ronca R, Presta M, Romagnoli R, Baraldi PG, Basso G. Porcù E, et al. Angiogenesis. 2013 Jul;16(3):647-62. doi: 10.1007/s10456-013-9343-z. Epub 2013 Mar 2. Angiogenesis. 2013. PMID: 23456551 Free article.

7

Synthesis and biological evaluation of imidazo[1,2-a]pyrimidines and imidazo[1,2-a]pyridines as new inhibitors of the Wnt/β-catenin signaling.

Cosimelli B, Laneri S, Ostacolo C, Sacchi A, Severi E, Porcù E, Rampazzo E, Moro E, Basso G, Viola G. Cosimelli B, et al. Among authors: porcu e. Eur J Med Chem. 2014 Aug 18;83:45-56. doi: 10.1016/j.ejmech.2014.05.071. Epub 2014 Jun 6. Eur J Med Chem. 2014. PMID: 24950489

8

Novel 9'-substituted-noscapines: synthesis with Suzuki cross-coupling, structure elucidation and biological evaluation.

Porcù E, Sipos A, Basso G, Hamel E, Bai R, Stempfer V, Udvardy A, Bényei AC, Schmidhammer H, Antus S, Viola G. Porcù E, et al. Eur J Med Chem. 2014 Sep 12;84:476-90. doi: 10.1016/j.ejmech.2014.07.050. Epub 2014 Jul 16. Eur J Med Chem. 2014. PMID: 25050880 Free PMC article.

9

Vascular disrupting activity of combretastatin analogues.

Porcù E, Salvador A, Primac I, Mitola S, Ronca R, Ravelli C, Bortolozzi R, Vedaldi D, Romagnoli R, Basso G, Viola G. Porcù E, et al. Vascul Pharmacol. 2016 Aug;83:78-89. doi: 10.1016/j.vph.2016.05.006. Epub 2016 May 25. Vascul Pharmacol. 2016. PMID: 27235861

10

The Novel Antitubulin Agent TR-764 Strongly Reduces Tumor Vasculature and Inhibits HIF-1α Activation.

Porcù E, Persano L, Ronca R, Mitola S, Bortolozzi R, Romagnoli R, Oliva P, Basso G, Viola G. Porcù E, et al. Sci Rep. 2016 Jun 13;6:27886. doi: 10.1038/srep27886. Sci Rep. 2016. PMID: 27292568 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

256 results

Search Page