Popowicz GM - Search Results

1

Novel Trypanocidal Inhibitors that Block Glycosome Biogenesis by Targeting PEX3-PEX19 Interaction.

Li M, Gaussmann S, Tippler B, Ott J, Popowicz GM, Schliebs W, Sattler M, Erdmann R, Kalel VC. Li M, et al. Among authors: popowicz gm. Front Cell Dev Biol. 2021 Dec 20;9:737159. doi: 10.3389/fcell.2021.737159. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34988071 Free PMC article.

2

Structural basis for the assembly of the Sxl-Unr translation regulatory complex.

Hennig J, Militti C, Popowicz GM, Wang I, Sonntag M, Geerlof A, Gabel F, Gebauer F, Sattler M. Hennig J, et al. Among authors: popowicz gm. Nature. 2014 Nov 13;515(7526):287-90. doi: 10.1038/nature13693. Epub 2014 Sep 7. Nature. 2014. PMID: 25209665

3

Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism.

Haslbeck V, Drazic A, Eckl JM, Alte F, Helmuth M, Popowicz G, Schmidt W, Braun F, Weiwad M, Fischer G, Gemmecker G, Sattler M, Striggow F, Groll M, Richter K. Haslbeck V, et al. Biosci Rep. 2015 Apr 20;35(3):e00210. doi: 10.1042/BSR20150042. Biosci Rep. 2015. PMID: 26182372 Free PMC article.

4

Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.

Dawidowski M, Emmanouilidis L, Kalel VC, Tripsianes K, Schorpp K, Hadian K, Kaiser M, Mäser P, Kolonko M, Tanghe S, Rodriguez A, Schliebs W, Erdmann R, Sattler M, Popowicz GM. Dawidowski M, et al. Among authors: popowicz gm. Science. 2017 Mar 31;355(6332):1416-1420. doi: 10.1126/science.aal1807. Science. 2017. PMID: 28360328

5

Inhibitors of glycosomal protein import provide new leads against trypanosomiasis.

Kalel VC, Emmanouilidis L, Dawidowski M, Schliebs W, Sattler M, Popowicz GM, Erdmann R. Kalel VC, et al. Among authors: popowicz gm. Microb Cell. 2017 Jul 3;4(7):229-232. doi: 10.15698/mic2017.07.581. Microb Cell. 2017. PMID: 28706938 Free PMC article.

6

Identification of small-molecule inhibitors of USP2a.

Tomala MD, Magiera-Mularz K, Kubica K, Krzanik S, Zieba B, Musielak B, Pustula M, Popowicz GM, Sattler M, Dubin G, Skalniak L, Holak TA. Tomala MD, et al. Among authors: popowicz gm. Eur J Med Chem. 2018 Apr 25;150:261-267. doi: 10.1016/j.ejmech.2018.03.009. Epub 2018 Mar 5. Eur J Med Chem. 2018. PMID: 29529503

7

Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity.

Brenke JK, Popowicz GM, Schorpp K, Rothenaigner I, Roesner M, Meininger I, Kalinski C, Ringelstetter L, R'kyek O, Jürjens G, Vincendeau M, Plettenburg O, Sattler M, Krappmann D, Hadian K. Brenke JK, et al. Among authors: popowicz gm. J Biol Chem. 2018 Aug 24;293(34):13191-13203. doi: 10.1074/jbc.RA118.002649. Epub 2018 Jun 27. J Biol Chem. 2018. PMID: 29950522 Free PMC article.

8

HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.

Pabis M, Popowicz GM, Stehle R, Fernández-Ramos D, Asami S, Warner L, García-Mauriño SM, Schlundt A, Martínez-Chantar ML, Díaz-Moreno I, Sattler M. Pabis M, et al. Among authors: popowicz gm. Nucleic Acids Res. 2019 Jan 25;47(2):1011-1029. doi: 10.1093/nar/gky1138. Nucleic Acids Res. 2019. PMID: 30418581 Free PMC article.

9

The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation.

Ostertag MS, Messias AC, Sattler M, Popowicz GM. Ostertag MS, et al. Among authors: popowicz gm. Structure. 2019 Feb 5;27(2):327-334.e3. doi: 10.1016/j.str.2018.10.005. Epub 2018 Nov 15. Structure. 2019. PMID: 30449689 Free article.

10

Come, sweet death: targeting glycosomal protein import for antitrypanosomal drug development.

Kalel VC, Mäser P, Sattler M, Erdmann R, Popowicz GM. Kalel VC, et al. Among authors: popowicz gm. Curr Opin Microbiol. 2018 Dec;46:116-122. doi: 10.1016/j.mib.2018.11.003. Epub 2018 Nov 24. Curr Opin Microbiol. 2018. PMID: 30481613 Review.

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