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AXL Expression on Homeostatic Resident Liver Macrophages Is Reduced in Cirrhosis Following GAS6 Production by Hepatic Stellate Cells.
Pop OT, Geng A, Flint E, Singanayagam A, Ercan C, Possamai L, Patel VC, Kuenzler P, Meier MA, Soysal S, Hruz P, Kollmar O, Tatham KC, Ward JK, Müllhaupt B, Weber A, Wendon J, Niess JH, Heim M, Semela D, Weston C, Antoniades CG, Terracciano LM, Triantafyllou E, Brenig RG, Bernsmeier C. Pop OT, et al. Cell Mol Gastroenterol Hepatol. 2023;16(1):17-37. doi: 10.1016/j.jcmgh.2023.03.007. Epub 2023 Mar 31. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37004869 Free PMC article.
Patients with acute-on-chronic liver failure have increased numbers of regulatory immune cells expressing the receptor tyrosine kinase MERTK.
Bernsmeier C, Pop OT, Singanayagam A, Triantafyllou E, Patel VC, Weston CJ, Curbishley S, Sadiq F, Vergis N, Khamri W, Bernal W, Auzinger G, Heneghan M, Ma Y, Jassem W, Heaton ND, Adams DH, Quaglia A, Thursz MR, Wendon J, Antoniades CG. Bernsmeier C, et al. Among authors: pop ot. Gastroenterology. 2015 Mar;148(3):603-615.e14. doi: 10.1053/j.gastro.2014.11.045. Epub 2014 Dec 3. Gastroenterology. 2015. PMID: 25479139 Free article.
Multivariate metabotyping of plasma predicts survival in patients with decompensated cirrhosis.
McPhail MJW, Shawcross DL, Lewis MR, Coltart I, Want EJ, Antoniades CG, Veselkov K, Triantafyllou E, Patel V, Pop O, Gomez-Romero M, Kyriakides M, Zia R, Abeles RD, Crossey MME, Jassem W, O'Grady J, Heaton N, Auzinger G, Bernal W, Quaglia A, Coen M, Nicholson JK, Wendon JA, Holmes E, Taylor-Robinson SD. McPhail MJW, et al. J Hepatol. 2016 May;64(5):1058-1067. doi: 10.1016/j.jhep.2016.01.003. Epub 2016 Jan 18. J Hepatol. 2016. PMID: 26795831 Free PMC article.
MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure.
Triantafyllou E, Pop OT, Possamai LA, Wilhelm A, Liaskou E, Singanayagam A, Bernsmeier C, Khamri W, Petts G, Dargue R, Davies SP, Tickle J, Yuksel M, Patel VC, Abeles RD, Stamataki Z, Curbishley SM, Ma Y, Wilson ID, Coen M, Woollard KJ, Quaglia A, Wendon J, Thursz MR, Adams DH, Weston CJ, Antoniades CG. Triantafyllou E, et al. Among authors: pop ot. Gut. 2018 Feb;67(2):333-347. doi: 10.1136/gutjnl-2016-313615. Epub 2017 Apr 27. Gut. 2018. PMID: 28450389 Free PMC article.
CD14+ CD15- HLA-DR- myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure.
Bernsmeier C, Triantafyllou E, Brenig R, Lebosse FJ, Singanayagam A, Patel VC, Pop OT, Khamri W, Nathwani R, Tidswell R, Weston CJ, Adams DH, Thursz MR, Wendon JA, Antoniades CG. Bernsmeier C, et al. Among authors: pop ot. Gut. 2018 Jun;67(6):1155-1167. doi: 10.1136/gutjnl-2017-314184. Epub 2017 Jun 7. Gut. 2018. PMID: 28592438 Free PMC article.
Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis.
Brenig R, Pop OT, Triantafyllou E, Geng A, Singanayagam A, Perez-Shibayama C, Besse L, Cupovic J, Künzler P, Boldanova T, Brand S, Semela D, Duong FH, Weston CJ, Ludewig B, Heim MH, Wendon J, Antoniades CG, Bernsmeier C. Brenig R, et al. Among authors: pop ot. Life Sci Alliance. 2019 Dec 10;3(1):e201900465. doi: 10.26508/lsa.201900465. Print 2020 Jan. Life Sci Alliance. 2019. PMID: 31822557 Free PMC article.
CD8+T cells from patients with cirrhosis display a phenotype that may contribute to cirrhosis-associated immune dysfunction.
Lebossé F, Gudd C, Tunc E, Singanayagam A, Nathwani R, Triantafyllou E, Pop O, Kumar N, Mukherjee S, Hou TZ, Quaglia A, Zoulim F, Wendon J, Dhar A, Thursz M, Antoniades CG, Khamri W. Lebossé F, et al. EBioMedicine. 2019 Nov;49:258-268. doi: 10.1016/j.ebiom.2019.10.011. Epub 2019 Oct 31. EBioMedicine. 2019. PMID: 31678004 Free PMC article.
47 results