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A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen.
Landegren N, Ishii N, Aranda-Guillén M, Gunnarsson HI, Sardh F, Hallgren Å, Ståhle M, Hagforsen E, Bradley M, Edqvist PD, Pontén F, Mäkitie O, Eidsmo L, Norlén L, Achour A, Dahlbom I, Korponay-Szabó I, Agardh D, Alimohammadi M, Eriksson D, Hashimoto T, Kämpe O. Landegren N, et al. Among authors: ponten f. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2100687118. doi: 10.1073/pnas.2100687118. Proc Natl Acad Sci U S A. 2021. PMID: 34911754 Free PMC article.
Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen.
Alimohammadi M, Dubois N, Sköldberg F, Hallgren A, Tardivel I, Hedstrand H, Haavik J, Husebye ES, Gustafsson J, Rorsman F, Meloni A, Janson C, Vialettes B, Kajosaari M, Egner W, Sargur R, Pontén F, Amoura Z, Grimfeld A, De Luca F, Betterle C, Perheentupa J, Kämpe O, Carel JC. Alimohammadi M, et al. Among authors: ponten f. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4396-401. doi: 10.1073/pnas.0809986106. Epub 2009 Feb 26. Proc Natl Acad Sci U S A. 2009. PMID: 19251657 Free PMC article.
PROX1 is a novel pathway-specific prognostic biomarker for high-grade astrocytomas; results from independent glioblastoma cohorts stratified by age and IDH mutation status.
Roodakker KR, Elsir T, Edqvist PD, Hägerstrand D, Carlson J, Lysiak M, Henriksson R, Pontén F, Rosell J, Söderkvist P, Stupp R, Tchougounova E, Nistér M, Malmström A, Smits A. Roodakker KR, et al. Among authors: ponten f. Oncotarget. 2016 Nov 8;7(45):72431-72442. doi: 10.18632/oncotarget.11957. Oncotarget. 2016. PMID: 27626492 Free PMC article.
Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis, and tissue microarray validation.
Botling J, Edlund K, Lohr M, Hellwig B, Holmberg L, Lambe M, Berglund A, Ekman S, Bergqvist M, Pontén F, König A, Fernandes O, Karlsson M, Helenius G, Karlsson C, Rahnenführer J, Hengstler JG, Micke P. Botling J, et al. Among authors: ponten f. Clin Cancer Res. 2013 Jan 1;19(1):194-204. doi: 10.1158/1078-0432.CCR-12-1139. Epub 2012 Oct 2. Clin Cancer Res. 2013. PMID: 23032747
SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas.
Magnusson K, de Wit M, Brennan DJ, Johnson LB, McGee SF, Lundberg E, Naicker K, Klinger R, Kampf C, Asplund A, Wester K, Gry M, Bjartell A, Gallagher WM, Rexhepaj E, Kilpinen S, Kallioniemi OP, Belt E, Goos J, Meijer G, Birgisson H, Glimelius B, Borrebaeck CA, Navani S, Uhlén M, O'Connor DP, Jirström K, Pontén F. Magnusson K, et al. Among authors: ponten f. Am J Surg Pathol. 2011 Jul;35(7):937-48. doi: 10.1097/PAS.0b013e31821c3dae. Am J Surg Pathol. 2011. PMID: 21677534
GAD1 is a biomarker for benign and malignant prostatic tissue.
Jaraj SJ, Augsten M, Häggarth L, Wester K, Pontén F, Ostman A, Egevad L. Jaraj SJ, et al. Among authors: ponten f. Scand J Urol Nephrol. 2011 Feb;45(1):39-45. doi: 10.3109/00365599.2010.521189. Epub 2010 Nov 22. Scand J Urol Nephrol. 2011. PMID: 21091088
308 results