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Senolytic CAR T cells reverse senescence-associated pathologies.
Amor C, Feucht J, Leibold J, Ho YJ, Zhu C, Alonso-Curbelo D, Mansilla-Soto J, Boyer JA, Li X, Giavridis T, Kulick A, Houlihan S, Peerschke E, Friedman SL, Ponomarev V, Piersigilli A, Sadelain M, Lowe SW. Amor C, et al. Among authors: ponomarev v. Nature. 2020 Jul;583(7814):127-132. doi: 10.1038/s41586-020-2403-9. Epub 2020 Jun 17. Nature. 2020. PMID: 32555459 Free PMC article.
Serial in vivo imaging of the targeted migration of human HSV-TK-transduced antigen-specific lymphocytes.
Koehne G, Doubrovin M, Doubrovina E, Zanzonico P, Gallardo HF, Ivanova A, Balatoni J, Teruya-Feldstein J, Heller G, May C, Ponomarev V, Ruan S, Finn R, Blasberg RG, Bornmann W, Riviere I, Sadelain M, O'Reilly RJ, Larson SM, Tjuvajev JG. Koehne G, et al. Among authors: ponomarev v. Nat Biotechnol. 2003 Apr;21(4):405-13. doi: 10.1038/nbt805. Epub 2003 Mar 24. Nat Biotechnol. 2003. PMID: 12652311
Adoptively transferred TRAIL+ T cells suppress GVHD and augment antitumor activity.
Ghosh A, Dogan Y, Moroz M, Holland AM, Yim NL, Rao UK, Young LF, Tannenbaum D, Masih D, Velardi E, Tsai JJ, Jenq RR, Penack O, Hanash AM, Smith OM, Piersanti K, Lezcano C, Murphy GF, Liu C, Palomba ML, Sauer MG, Sadelain M, Ponomarev V, van den Brink MR. Ghosh A, et al. Among authors: ponomarev v. J Clin Invest. 2013 Jun;123(6):2654-62. doi: 10.1172/JCI66301. Epub 2013 May 15. J Clin Invest. 2013. PMID: 23676461 Free PMC article.
Therapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1.
Dao T, Pankov D, Scott A, Korontsvit T, Zakhaleva V, Xu Y, Xiang J, Yan S, de Morais Guerreiro MD, Veomett N, Dubrovsky L, Curcio M, Doubrovina E, Ponomarev V, Liu C, O'Reilly RJ, Scheinberg DA. Dao T, et al. Among authors: ponomarev v. Nat Biotechnol. 2015 Oct;33(10):1079-86. doi: 10.1038/nbt.3349. Epub 2015 Sep 21. Nat Biotechnol. 2015. PMID: 26389576 Free PMC article.
329 results