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Engineering-specific pharmacological binding sites for peptidyl inhibitors of potassium channels into KcsA.
Legros C, Schulze C, Garcia ML, Bougis PE, Martin-Eauclaire MF, Pongs O. Legros C, et al. Among authors: pongs o. Biochemistry. 2002 Dec 24;41(51):15369-75. doi: 10.1021/bi026264a. Biochemistry. 2002. PMID: 12484776
., Farrell, A. M., Darbon, H., Bougis, P. E., Martin-Eauclaire, M. F., and Pongs, O. (2000) J. Biol. Chem. 275, 16918-16924]. This approach opened the way to investigate whether sequence differences in subregion I of Kv1 channels correlate with the distinct pharmaco …
., Farrell, A. M., Darbon, H., Bougis, P. E., Martin-Eauclaire, M. F., and Pongs, O. (2000) J. Biol. Chem. 275, 16918-16924]. …
A structural link between inactivation and block of a K+ channel.
Ader C, Schneider R, Hornig S, Velisetty P, Wilson EM, Lange A, Giller K, Ohmert I, Martin-Eauclaire MF, Trauner D, Becker S, Pongs O, Baldus M. Ader C, et al. Among authors: pongs o. Nat Struct Mol Biol. 2008 Jun;15(6):605-12. doi: 10.1038/nsmb.1430. Epub 2008 May 18. Nat Struct Mol Biol. 2008. PMID: 18488040
MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity.
Rosso JP, Schwarz JR, Diaz-Bustamante M, Céard B, Gutiérrez JM, Kneussel M, Pongs O, Bosmans F, Bougis PE. Rosso JP, et al. Among authors: pongs o. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):E891-900. doi: 10.1073/pnas.1415488112. Epub 2015 Feb 9. Proc Natl Acad Sci U S A. 2015. PMID: 25675485 Free PMC article.
247 results