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From PROTAC to inhibitor: Structure-guided discovery of potent and orally bioavailable BET inhibitors.
Koravovic M, Mayasundari A, Tasic G, Keramatnia F, Stachowski TR, Cui H, Chai SC, Jonchere B, Yang L, Li Y, Fu X, Hiltenbrand R, Paul L, Mishra V, Klco JM, Roussel MF, Pomerantz WC, Fischer M, Rankovic Z, Savic V. Koravovic M, et al. Among authors: pomerantz wc. Eur J Med Chem. 2023 May 5;251:115246. doi: 10.1016/j.ejmech.2023.115246. Epub 2023 Mar 4. Eur J Med Chem. 2023. PMID: 36898329 Free PMC article.
Genetically encoded discovery of perfluoroaryl macrocycles that bind to albumin and exhibit extended circulation in vivo.
Wong JYK, Ekanayake AI, Kharchenko S, Kirberger SE, Qiu R, Kelich P, Sarkar S, Li J, Fernandez KX, Alvizo-Paez ER, Miao J, Kalhor-Monfared S, John JD, Kang H, Choi H, Nuss JM, Vederas JC, Lin YS, Macauley MS, Vukovic L, Pomerantz WCK, Derda R. Wong JYK, et al. Among authors: pomerantz wck. Nat Commun. 2023 Sep 13;14(1):5654. doi: 10.1038/s41467-023-41427-y. Nat Commun. 2023. PMID: 37704629 Free PMC article.
In situ monitoring of backbone thioester exchange by 19F NMR.
Pomerantz WC, Hadley EB, Fry CG, Gellman SH. Pomerantz WC, et al. Chembiochem. 2009 Sep 4;10(13):2177-81. doi: 10.1002/cbic.200900380. Chembiochem. 2009. PMID: 19644993 Free PMC article. No abstract available.
A rationally designed aldolase foldamer.
Müller MM, Windsor MA, Pomerantz WC, Gellman SH, Hilvert D. Müller MM, et al. Among authors: pomerantz wc. Angew Chem Int Ed Engl. 2009;48(5):922-5. doi: 10.1002/anie.200804996. Angew Chem Int Ed Engl. 2009. PMID: 19090515 Free PMC article. No abstract available.
Antifungal activity from 14-helical beta-peptides.
Karlsson AJ, Pomerantz WC, Weisblum B, Gellman SH, Palecek SP. Karlsson AJ, et al. Among authors: pomerantz wc. J Am Chem Soc. 2006 Oct 4;128(39):12630-1. doi: 10.1021/ja064630y. J Am Chem Soc. 2006. PMID: 17002340
95 results