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KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma.
Kim YY, Gryder BE, Sinniah R, Peach ML, Shern JF, Abdelmaksoud A, Pomella S, Woldemichael GM, Stanton BZ, Milewski D, Barchi JJ Jr, Schneekloth JS Jr, Chari R, Kowalczyk JT, Shenoy SR, Evans JR, Song YK, Wang C, Wen X, Chou HC, Gangalapudi V, Esposito D, Jones J, Procter L, O'Neill M, Jenkins LM, Tarasova NI, Wei JS, McMahon JB, O'Keefe BR, Hawley RG, Khan J. Kim YY, et al. Among authors: pomella s. Nat Commun. 2024 Feb 24;15(1):1703. doi: 10.1038/s41467-024-45902-y. Nat Commun. 2024. PMID: 38402212 Free PMC article.
MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57Kip2 targeting.
Pomella S, Cassandri M, D'Archivio L, Porrazzo A, Cossetti C, Phelps D, Perrone C, Pezzella M, Cardinale A, Wachtel M, Aloisi S, Milewski D, Colletti M, Sreenivas P, Walters ZS, Barillari G, Di Giannatale A, Milano GM, De Stefanis C, Alaggio R, Rodriguez-Rodriguez S, Carlesso N, Vakoc CR, Velardi E, Schafer BW, Guccione E, Gatz SA, Wasti A, Yohe M, Ignatius M, Quintarelli C, Shipley J, Miele L, Khan J, Houghton PJ, Marampon F, Gryder BE, De Angelis B, Locatelli F, Rota R. Pomella S, et al. Nat Commun. 2023 Dec 15;14(1):8373. doi: 10.1038/s41467-023-44130-0. Nat Commun. 2023. PMID: 38102140 Free PMC article.
The Combination of Immune Checkpoint Blockade with Tumor Vessel Normalization as a Promising Therapeutic Strategy for Breast Cancer: An Overview of Preclinical and Clinical Studies.
Melaiu O, Vanni G, Portarena I, Pistolese CA, Anemona L, Pomella S, Bei R, Buonomo OC, Roselli M, Mauriello A, Barillari G. Melaiu O, et al. Among authors: pomella s. Int J Mol Sci. 2023 Feb 6;24(4):3226. doi: 10.3390/ijms24043226. Int J Mol Sci. 2023. PMID: 36834641 Free PMC article. Review.
Spermine oxidase induces DNA damage and sensitizes fusion negative rhabdomyosarcoma cells to irradiation.
Perrone C, Pomella S, Cassandri M, Pezzella M, Giuliani S, Gasperi T, Porrazzo A, Alisi A, Pastore A, Codenotti S, Fanzani A, Barillari G, Conti LA, De Angelis B, Quintarelli C, Mariottini P, Locatelli F, Marampon F, Rota R, Cervelli M. Perrone C, et al. Among authors: pomella s. Front Cell Dev Biol. 2023 Jan 23;11:1061570. doi: 10.3389/fcell.2023.1061570. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 36755974 Free PMC article.
The botanical drug PBI-05204, a supercritical CO2 extract of Nerium oleander, sensitizes alveolar and embryonal rhabdomyosarcoma to radiotherapy in vitro and in vivo.
Vaccaro S, Rossetti A, Porrazzo A, Camero S, Cassandri M, Pomella S, Tomaciello M, Macioce G, Pedini F, Barillari G, Marchese C, Rota R, Cenci G, Tombolini M, Newman RA, Yang P, Codenotti S, Fanzani A, Megiorni F, Festuccia C, Minniti G, Gravina GL, Vulcano F, Milazzo L, Marampon F. Vaccaro S, et al. Among authors: pomella s. Front Pharmacol. 2022 Dec 1;13:1071176. doi: 10.3389/fphar.2022.1071176. eCollection 2022. Front Pharmacol. 2022. PMID: 36532747 Free PMC article.
Translational Implications for Radiosensitizing Strategies in Rhabdomyosarcoma.
Pomella S, Porrazzo A, Cassandri M, Camero S, Codenotti S, Milazzo L, Vulcano F, Barillari G, Cenci G, Marchese C, Fanzani A, Megiorni F, Rota R, Marampon F. Pomella S, et al. Int J Mol Sci. 2022 Oct 31;23(21):13281. doi: 10.3390/ijms232113281. Int J Mol Sci. 2022. PMID: 36362070 Free PMC article. Review.
Radioresistance in rhabdomyosarcomas: Much more than a question of dose.
Camero S, Cassandri M, Pomella S, Milazzo L, Vulcano F, Porrazzo A, Barillari G, Marchese C, Codenotti S, Tomaciello M, Rota R, Fanzani A, Megiorni F, Marampon F. Camero S, et al. Among authors: pomella s. Front Oncol. 2022 Sep 29;12:1016894. doi: 10.3389/fonc.2022.1016894. eCollection 2022. Front Oncol. 2022. PMID: 36248991 Free PMC article. Review.
33 results