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CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation.
Krajewska M, Dries R, Grassetti AV, Dust S, Gao Y, Huang H, Sharma B, Day DS, Kwiatkowski N, Pomaville M, Dodd O, Chipumuro E, Zhang T, Greenleaf AL, Yuan GC, Gray NS, Young RA, Geyer M, Gerber SA, George RE. Krajewska M, et al. Among authors: pomaville m. Nat Commun. 2019 Apr 15;10(1):1757. doi: 10.1038/s41467-019-09703-y. Nat Commun. 2019. PMID: 30988284 Free PMC article.
The Evolutionarily Conserved C-terminal Domains in the Mammalian Retinoblastoma Tumor Suppressor Family Serve as Dual Regulators of Protein Stability and Transcriptional Potency.
Sengupta S, Lingnurkar R, Carey TS, Pomaville M, Kar P, Feig M, Wilson CA, Knott JG, Arnosti DN, Henry RW. Sengupta S, et al. Among authors: pomaville m. J Biol Chem. 2015 Jun 5;290(23):14462-75. doi: 10.1074/jbc.M114.599993. Epub 2015 Apr 22. J Biol Chem. 2015. PMID: 25903125 Free PMC article.
A new dawn for the study of cell type evolution.
Pomaville MB, Sattler SM, Abitua PB. Pomaville MB, et al. Development. 2024 May 1;151(9):dev200884. doi: 10.1242/dev.200884. Epub 2024 May 9. Development. 2024. PMID: 38722217 Review.
Small-molecule inhibition of the METTL3/METTL14 complex suppresses neuroblastoma tumor growth and promotes differentiation.
Pomaville M, Chennakesavalu M, Wang P, Jiang Z, Sun HL, Ren P, Borchert R, Gupta V, Ye C, Ge R, Zhu Z, Brodnik M, Zhong Y, Moore K, Salwen H, George RE, Krajewska M, Chlenski A, Applebaum MA, He C, Cohn SL. Pomaville M, et al. Cell Rep. 2024 Apr 30;43(5):114165. doi: 10.1016/j.celrep.2024.114165. Online ahead of print. Cell Rep. 2024. PMID: 38691450 Free article.
Cell Context is the third axis of synergy for the combination of ATR inhibition and cisplatin in Ewing sarcoma.
Jess J, Sorensen KM, Boguslawski EA, Stout MC, Madaj ZB, Caiello BP, Pomaville M, Wilson ER, Kinn-Gurzo SS, Parker CC, Veluvolu SM, Brysgel TV, Kaufman R, Kitchen-Goosen SM, Gedminas JM, Grohar PJ. Jess J, et al. Among authors: pomaville m. Clin Cancer Res. 2024 Mar 20. doi: 10.1158/1078-0432.CCR-23-3063. Online ahead of print. Clin Cancer Res. 2024. PMID: 38506712
Characterization of PARP6 Function in Knockout Mice and Patients with Developmental Delay.
Vermehren-Schmaedick A, Huang JY, Levinson M, Pomaville MB, Reed S, Bellus GA, Gilbert F, Keren B, Heron D, Haye D, Janello C, Makowski C, Danhauser K, Fedorov LM, Haack TB, Wright KM, Cohen MS. Vermehren-Schmaedick A, et al. Among authors: pomaville mb. Cells. 2021 May 22;10(6):1289. doi: 10.3390/cells10061289. Cells. 2021. PMID: 34067418 Free PMC article.
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