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Page 1
TFEB induces mitochondrial itaconate synthesis to suppress bacterial growth in macrophages.
Schuster EM, Epple MW, Glaser KM, Mihlan M, Lucht K, Zimmermann JA, Bremser A, Polyzou A, Obier N, Cabezas-Wallscheid N, Trompouki E, Ballabio A, Vogel J, Buescher JM, Westermann AJ, Rambold AS. Schuster EM, et al. Among authors: polyzou a. Nat Metab. 2022 Jul;4(7):856-866. doi: 10.1038/s42255-022-00605-w. Epub 2022 Jul 21. Nat Metab. 2022. PMID: 35864246 Free PMC article.
A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways.
Piragyte I, Clapes T, Polyzou A, Klein Geltink RI, Lefkopoulos S, Yin N, Cauchy P, Curtis JD, Klaeylé L, Langa X, Beckmann CCA, Wlodarski MW, Müller P, Van Essen D, Rambold A, Kapp FG, Mione M, Buescher JM, Pearce EL, Polyzos A, Trompouki E. Piragyte I, et al. Among authors: polyzou a. Nat Commun. 2018 Aug 6;9(1):3090. doi: 10.1038/s41467-018-05311-4. Nat Commun. 2018. PMID: 30082823 Free PMC article.
Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.
Clapes T, Polyzou A, Prater P, Sagar, Morales-Hernández A, Ferrarini MG, Kehrer N, Lefkopoulos S, Bergo V, Hummel B, Obier N, Maticzka D, Bridgeman A, Herman JS, Ilik I, Klaeylé L, Rehwinkel J, McKinney-Freeman S, Backofen R, Akhtar A, Cabezas-Wallscheid N, Sawarkar R, Rebollo R, Grün D, Trompouki E. Clapes T, et al. Among authors: polyzou a. Nat Cell Biol. 2021 Jul;23(7):704-717. doi: 10.1038/s41556-021-00707-9. Epub 2021 Jul 12. Nat Cell Biol. 2021. PMID: 34253898 Free PMC article.
Publisher Correction: Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.
Clapes T, Polyzou A, Prater P, Sagar, Morales-Hernández A, Ferrarini MG, Kehrer N, Lefkopoulos S, Bergo V, Hummel B, Obier N, Maticzka D, Bridgeman A, Herman JS, Ilik I, Klaeylé L, Rehwinkel J, McKinney-Freeman S, Backofen R, Akhtar A, Cabezas-Wallscheid N, Sawarkar R, Rebollo R, Grün D, Trompouki E. Clapes T, et al. Among authors: polyzou a. Nat Cell Biol. 2021 Dec;23(12):1338. doi: 10.1038/s41556-021-00785-9. Nat Cell Biol. 2021. PMID: 34611323 Free PMC article. No abstract available.
Repetitive Elements Trigger RIG-I-like Receptor Signaling that Regulates the Emergence of Hematopoietic Stem and Progenitor Cells.
Lefkopoulos S, Polyzou A, Derecka M, Bergo V, Clapes T, Cauchy P, Jerez-Longres C, Onishi-Seebacher M, Yin N, Martagon-Calderón NA, Potts KS, Klaeylé L, Liu F, Bowman TV, Jenuwein T, Mione MC, Trompouki E. Lefkopoulos S, et al. Among authors: polyzou a. Immunity. 2020 Nov 17;53(5):934-951.e9. doi: 10.1016/j.immuni.2020.10.007. Epub 2020 Nov 6. Immunity. 2020. PMID: 33159854 Free article.
RASSF1A disrupts the NOTCH signaling axis via SNURF/RNF4-mediated ubiquitination of HES1.
Papaspyropoulos A, Angelopoulou A, Mourkioti I, Polyzou A, Pankova D, Toskas K, Lanfredini S, Pantazaki AA, Lagopati N, Kotsinas A, Evangelou K, Chronopoulos E, O'Neill E, Gorgoulis V. Papaspyropoulos A, et al. Among authors: polyzou a. EMBO Rep. 2022 Feb 3;23(2):e51287. doi: 10.15252/embr.202051287. Epub 2021 Dec 13. EMBO Rep. 2022. PMID: 34897944 Free PMC article.
A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization.
Zampetidis CP, Galanos P, Angelopoulou A, Zhu Y, Polyzou A, Karamitros T, Kotsinas A, Lagopati N, Mourkioti I, Mirzazadeh R, Polyzos A, Garnerone S, Mizi A, Gusmao EG, Sofiadis K, Gál Z, Larsen DH, Pefani DE, Demaria M, Tsirigos A, Crosetto N, Maya-Mendoza A, Papaspyropoulos A, Evangelou K, Bartek J, Papantonis A, Gorgoulis VG. Zampetidis CP, et al. Among authors: polyzou a. Mol Cell. 2021 Dec 2;81(23):4907-4923.e8. doi: 10.1016/j.molcel.2021.10.017. Epub 2021 Nov 17. Mol Cell. 2021. PMID: 34793711 Free article.
Pulmonary infection by SARS-CoV-2 induces senescence accompanied by an inflammatory phenotype in severe COVID-19: possible implications for viral mutagenesis.
Evangelou K, Veroutis D, Paschalaki K, Foukas PG, Lagopati N, Dimitriou M, Papaspyropoulos A, Konda B, Hazapis O, Polyzou A, Havaki S, Kotsinas A, Kittas C, Tzioufas AG, de Leval L, Vassilakos D, Tsiodras S, Stripp BR, Papantonis A, Blandino G, Karakasiliotis I, Barnes PJ, Gorgoulis VG. Evangelou K, et al. Among authors: polyzou a. Eur Respir J. 2022 Aug 18;60(2):2102951. doi: 10.1183/13993003.02951-2021. Print 2022 Aug. Eur Respir J. 2022. PMID: 35086840 Free PMC article.
Sample pooling strategies for SARS-CoV-2 detection.
Lagopati N, Tsioli P, Mourkioti I, Polyzou A, Papaspyropoulos A, Zafiropoulos A, Evangelou K, Sourvinos G, Gorgoulis VG. Lagopati N, et al. Among authors: polyzou a. J Virol Methods. 2021 Mar;289:114044. doi: 10.1016/j.jviromet.2020.114044. Epub 2020 Dec 11. J Virol Methods. 2021. PMID: 33316285 Free PMC article. Review.
Evaluation of senescent cells in intervertebral discs by lipofuscin staining.
Veroutis D, Kouroumalis A, Lagopati N, Polyzou A, Chamilos C, Papadodima S, Evangelou K, Gorgoulis VG, Kletsas D. Veroutis D, et al. Among authors: polyzou a. Mech Ageing Dev. 2021 Oct;199:111564. doi: 10.1016/j.mad.2021.111564. Epub 2021 Aug 30. Mech Ageing Dev. 2021. PMID: 34474077
30 results