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Efficient reduction of the formation of by-products and improvement of production yield of 2,3-butanediol by a combined deletion of alcohol dehydrogenase, acetate kinase-phosphotransacetylase, and lactate dehydrogenase genes in metabolically engineered Klebsiella oxytoca in mineral salts medium.
Jantama K, Polyiam P, Khunnonkwao P, Chan S, Sangproo M, Khor K, Jantama SS, Kanchanatawee S. Jantama K, et al. Among authors: polyiam p. Metab Eng. 2015 Jul;30:16-26. doi: 10.1016/j.ymben.2015.04.004. Epub 2015 Apr 17. Metab Eng. 2015. PMID: 25895450