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mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.
Garros-Regulez L, Aldaz P, Arrizabalaga O, Moncho-Amor V, Carrasco-Garcia E, Manterola L, Moreno-Cugnon L, Barrena C, Villanua J, Ruiz I, Pollard S, Lovell-Badge R, Sampron N, Garcia I, Matheu A. Garros-Regulez L, et al. Among authors: pollard s. Expert Opin Ther Targets. 2016;20(4):393-405. doi: 10.1517/14728222.2016.1151002. Expert Opin Ther Targets. 2016. PMID: 26878385 Free PMC article.
Oncogenic activity of SOX1 in glioblastoma.
Garcia I, Aldaregia J, Marjanovic Vicentic J, Aldaz P, Moreno-Cugnon L, Torres-Bayona S, Carrasco-Garcia E, Garros-Regulez L, Egaña L, Rubio A, Pollard S, Stevanovic M, Sampron N, Matheu A. Garcia I, et al. Among authors: pollard s. Sci Rep. 2017 Apr 20;7:46575. doi: 10.1038/srep46575. Sci Rep. 2017. PMID: 28425506 Free PMC article.
Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators.
Bulstrode H, Johnstone E, Marques-Torrejon MA, Ferguson KM, Bressan RB, Blin C, Grant V, Gogolok S, Gangoso E, Gagrica S, Ender C, Fotaki V, Sproul D, Bertone P, Pollard SM. Bulstrode H, et al. Among authors: pollard sm. Genes Dev. 2017 Apr 15;31(8):757-773. doi: 10.1101/gad.293027.116. Epub 2017 May 2. Genes Dev. 2017. PMID: 28465359 Free PMC article.
High expression of MKP1/DUSP1 counteracts glioma stem cell activity and mediates HDAC inhibitor response.
Arrizabalaga O, Moreno-Cugnon L, Auzmendi-Iriarte J, Aldaz P, Ibanez de Caceres I, Garros-Regulez L, Moncho-Amor V, Torres-Bayona S, Pernía O, Pintado-Berninches L, Carrasco-Ramirez P, Cortes-Sempere M, Rosas R, Sanchez-Gomez P, Ruiz I, Caren H, Pollard S, Garcia I, Sacido AA, Lovell-Badge R, Belda-Iniesta C, Sampron N, Perona R, Matheu A. Arrizabalaga O, et al. Among authors: pollard s. Oncogenesis. 2017 Dec 14;6(12):401. doi: 10.1038/s41389-017-0003-9. Oncogenesis. 2017. PMID: 29284798 Free PMC article.
A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1.
Danovi D, Folarin A, Gogolok S, Ender C, Elbatsh AM, Engström PG, Stricker SH, Gagrica S, Georgian A, Yu D, U KP, Harvey KJ, Ferretti P, Paddison PJ, Preston JE, Abbott NJ, Bertone P, Smith A, Pollard SM. Danovi D, et al. Among authors: pollard sm. PLoS One. 2013 Oct 30;8(10):e77053. doi: 10.1371/journal.pone.0077053. eCollection 2013. PLoS One. 2013. PMID: 24204733 Free PMC article.
546 results