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Central nervous system regeneration is driven by microglia necroptosis and repopulation.
Lloyd AF, Davies CL, Holloway RK, Labrak Y, Ireland G, Carradori D, Dillenburg A, Borger E, Soong D, Richardson JC, Kuhlmann T, Williams A, Pollard JW, des Rieux A, Priller J, Miron VE. Lloyd AF, et al. Among authors: pollard jw. Nat Neurosci. 2019 Jul;22(7):1046-1052. doi: 10.1038/s41593-019-0418-z. Epub 2019 Jun 10. Nat Neurosci. 2019. PMID: 31182869 Free PMC article.
Macrophages inhibit and enhance endometriosis depending on their origin.
Hogg C, Panir K, Dhami P, Rosser M, Mack M, Soong D, Pollard JW, Jenkins SJ, Horne AW, Greaves E. Hogg C, et al. Among authors: pollard jw. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2013776118. doi: 10.1073/pnas.2013776118. Proc Natl Acad Sci U S A. 2021. PMID: 33536334 Free PMC article.
Targeting macrophages: therapeutic approaches in cancer.
Cassetta L, Pollard JW. Cassetta L, et al. Among authors: pollard jw. Nat Rev Drug Discov. 2018 Dec;17(12):887-904. doi: 10.1038/nrd.2018.169. Epub 2018 Oct 26. Nat Rev Drug Discov. 2018. PMID: 30361552 Review.
Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets.
Cassetta L, Fragkogianni S, Sims AH, Swierczak A, Forrester LM, Zhang H, Soong DYH, Cotechini T, Anur P, Lin EY, Fidanza A, Lopez-Yrigoyen M, Millar MR, Urman A, Ai Z, Spellman PT, Hwang ES, Dixon JM, Wiechmann L, Coussens LM, Smith HO, Pollard JW. Cassetta L, et al. Among authors: pollard jw. Cancer Cell. 2019 Apr 15;35(4):588-602.e10. doi: 10.1016/j.ccell.2019.02.009. Epub 2019 Mar 28. Cancer Cell. 2019. PMID: 30930117 Free PMC article.
DKK1 drives immune suppressive phenotypes in intrahepatic cholangiocarcinoma and can be targeted with anti-DKK1 therapeutic DKN-01.
Jarman EJ, Horcas-Lopez M, Waddell SH, MacMaster S, Gournopanos K, Soong DYH, Musialik KI, Tsokkou P, Ng ME, Cambridge WA, Wilson DH, Kagey MH, Newman W, Pollard JW, Boulter L. Jarman EJ, et al. Among authors: pollard jw. Liver Int. 2023 Jan;43(1):208-220. doi: 10.1111/liv.15383. Epub 2022 Sep 15. Liver Int. 2023. PMID: 35924447 Free PMC article.
Immune cell promotion of metastasis.
Kitamura T, Qian BZ, Pollard JW. Kitamura T, et al. Among authors: pollard jw. Nat Rev Immunol. 2015 Feb;15(2):73-86. doi: 10.1038/nri3789. Nat Rev Immunol. 2015. PMID: 25614318 Free PMC article. Review.
291 results