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The application of in vitro methods to safety pharmacology.
Wakefield ID, Pollard C, Redfern WS, Hammond TG, Valentin JP. Wakefield ID, et al. Among authors: pollard c. Fundam Clin Pharmacol. 2002 Jun;16(3):209-18. doi: 10.1046/j.1472-8206.2002.00099.x. Fundam Clin Pharmacol. 2002. PMID: 12165068 Review.
Use of in vitro methods to predict QT prolongation.
Hammond TG, Pollard CE. Hammond TG, et al. Among authors: pollard ce. Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):446-50. doi: 10.1016/j.taap.2005.03.022. Toxicol Appl Pharmacol. 2005. PMID: 16023163 Review.
In vitro models of proarrhythmia.
Lawrence CL, Pollard CE, Hammond TG, Valentin JP. Lawrence CL, et al. Among authors: pollard ce. Br J Pharmacol. 2008 Aug;154(7):1516-22. doi: 10.1038/bjp.2008.195. Epub 2008 Jun 2. Br J Pharmacol. 2008. PMID: 18516075 Free PMC article. Review.
A framework to assess the translation of safety pharmacology data to humans.
Valentin JP, Bialecki R, Ewart L, Hammond T, Leishmann D, Lindgren S, Martinez V, Pollard C, Redfern W, Wallis R. Valentin JP, et al. Among authors: pollard c. J Pharmacol Toxicol Methods. 2009 Sep-Oct;60(2):152-8. doi: 10.1016/j.vascn.2009.05.011. Epub 2009 Jul 17. J Pharmacol Toxicol Methods. 2009. PMID: 19616110
Safety pharmacology--a progressive approach.
Redfern WS, Wakefield ID, Prior H, Pollard CE, Hammond TG, Valentin JP. Redfern WS, et al. Fundam Clin Pharmacol. 2002 Jun;16(3):161-73. doi: 10.1046/j.1472-8206.2002.00098.x. Fundam Clin Pharmacol. 2002. PMID: 12165064
How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?
Laverty H, Benson C, Cartwright E, Cross M, Garland C, Hammond T, Holloway C, McMahon N, Milligan J, Park B, Pirmohamed M, Pollard C, Radford J, Roome N, Sager P, Singh S, Suter T, Suter W, Trafford A, Volders P, Wallis R, Weaver R, York M, Valentin J. Laverty H, et al. Among authors: pollard c. Br J Pharmacol. 2011 Jun;163(4):675-93. doi: 10.1111/j.1476-5381.2011.01255.x. Br J Pharmacol. 2011. PMID: 21306581 Free PMC article. Review.
774 results