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Wilson disease protein ATP7B utilizes lysosomal exocytosis to maintain copper homeostasis.
Polishchuk EV, Concilli M, Iacobacci S, Chesi G, Pastore N, Piccolo P, Paladino S, Baldantoni D, van IJzendoorn SC, Chan J, Chang CJ, Amoresano A, Pane F, Pucci P, Tarallo A, Parenti G, Brunetti-Pierri N, Settembre C, Ballabio A, Polishchuk RS. Polishchuk EV, et al. Among authors: polishchuk rs. Dev Cell. 2014 Jun 23;29(6):686-700. doi: 10.1016/j.devcel.2014.04.033. Epub 2014 Jun 5. Dev Cell. 2014. PMID: 24909901 Free PMC article.
The emerging role of lysosomes in copper homeostasis.
Polishchuk EV, Polishchuk RS. Polishchuk EV, et al. Among authors: polishchuk rs. Metallomics. 2016 Sep 1;8(9):853-62. doi: 10.1039/c6mt00058d. Epub 2016 Jun 24. Metallomics. 2016. PMID: 27339113 Review.
Activation of Autophagy, Observed in Liver Tissues From Patients With Wilson Disease and From ATP7B-Deficient Animals, Protects Hepatocytes From Copper-Induced Apoptosis.
Polishchuk EV, Merolla A, Lichtmannegger J, Romano A, Indrieri A, Ilyechova EY, Concilli M, De Cegli R, Crispino R, Mariniello M, Petruzzelli R, Ranucci G, Iorio R, Pietrocola F, Einer C, Borchard S, Zibert A, Schmidt HH, Di Schiavi E, Puchkova LV, Franco B, Kroemer G, Zischka H, Polishchuk RS. Polishchuk EV, et al. Among authors: polishchuk rs. Gastroenterology. 2019 Mar;156(4):1173-1189.e5. doi: 10.1053/j.gastro.2018.11.032. Epub 2018 Nov 17. Gastroenterology. 2019. PMID: 30452922
Molecular determinants of ER-Golgi contacts identified through a new FRET-FLIM system.
Venditti R, Rega LR, Masone MC, Santoro M, Polishchuk E, Sarnataro D, Paladino S, D'Auria S, Varriale A, Olkkonen VM, Di Tullio G, Polishchuk R, De Matteis MA. Venditti R, et al. J Cell Biol. 2019 Mar 4;218(3):1055-1065. doi: 10.1083/jcb.201812020. Epub 2019 Jan 18. J Cell Biol. 2019. PMID: 30659100 Free PMC article.
145 results