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Anticancer 5-arylidene-2-(4-hydroxyphenyl)aminothiazol-4(5H)-ones as tubulin inhibitors.
Rehulka J, Subtelna I, Kryshchyshyn-Dylevych A, Cherniienko A, Ivanova A, Matveieva M, Polishchuk P, Gurska S, Hajduch M, Zagrijtschuk O, Dzubak P, Lesyk R. Rehulka J, et al. Among authors: polishchuk p. Arch Pharm (Weinheim). 2022 Dec;355(12):e2200419. doi: 10.1002/ardp.202200419. Epub 2022 Sep 15. Arch Pharm (Weinheim). 2022. PMID: 36109178
Synthesis and biological evaluation of cis-restrained carbocyclic combretastatin A-4 analogs: Influence of the ring size and saturation on cytotoxic properties.
Nowikow C, Fuerst R, Kauderer M, Dank C, Schmid W, Hajduch M, Rehulka J, Gurska S, Mokshyna O, Polishchuk P, Zupkó I, Dzubak P, Rinner U. Nowikow C, et al. Among authors: polishchuk p. Bioorg Med Chem. 2019 Oct 1;27(19):115032. doi: 10.1016/j.bmc.2019.07.048. Epub 2019 Jul 29. Bioorg Med Chem. 2019. PMID: 31401010
Benchmarks for interpretation of QSAR models.
Matveieva M, Polishchuk P. Matveieva M, et al. Among authors: polishchuk p. J Cheminform. 2021 May 26;13(1):41. doi: 10.1186/s13321-021-00519-x. J Cheminform. 2021. PMID: 34039411 Free PMC article.
Triazole-based estradiol dimers prepared via CuAAC from 17α-ethinyl estradiol with five-atom linkers causing G2/M arrest and tubulin inhibition.
Jurášek M, Řehulka J, Hrubá L, Ivanová A, Gurská S, Mokshyna O, Trousil P, Huml L, Polishchuk P, Hajdúch M, Drašar PB, Džubák P. Jurášek M, et al. Among authors: polishchuk p. Bioorg Chem. 2023 Feb;131:106334. doi: 10.1016/j.bioorg.2022.106334. Epub 2022 Dec 23. Bioorg Chem. 2023. PMID: 36592487 Free article.
44 results