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Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells.
Eicher AK, Kechele DO, Sundaram N, Berns HM, Poling HM, Haines LE, Sanchez JG, Kishimoto K, Krishnamurthy M, Han L, Zorn AM, Helmrath MA, Wells JM. Eicher AK, et al. Among authors: poling hm. Cell Stem Cell. 2022 Jan 6;29(1):36-51.e6. doi: 10.1016/j.stem.2021.10.010. Epub 2021 Dec 1. Cell Stem Cell. 2022. PMID: 34856121 Free PMC article.
An in vivo model of human small intestine using pluripotent stem cells.
Watson CL, Mahe MM, Múnera J, Howell JC, Sundaram N, Poling HM, Schweitzer JI, Vallance JE, Mayhew CN, Sun Y, Grabowski G, Finkbeiner SR, Spence JR, Shroyer NF, Wells JM, Helmrath MA. Watson CL, et al. Among authors: poling hm. Nat Med. 2014 Nov;20(11):1310-4. doi: 10.1038/nm.3737. Epub 2014 Oct 19. Nat Med. 2014. PMID: 25326803 Free PMC article.
Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system.
Workman MJ, Mahe MM, Trisno S, Poling HM, Watson CL, Sundaram N, Chang CF, Schiesser J, Aubert P, Stanley EG, Elefanty AG, Miyaoka Y, Mandegar MA, Conklin BR, Neunlist M, Brugmann SA, Helmrath MA, Wells JM. Workman MJ, et al. Among authors: poling hm. Nat Med. 2017 Jan;23(1):49-59. doi: 10.1038/nm.4233. Epub 2016 Nov 21. Nat Med. 2017. PMID: 27869805 Free PMC article.
In Vivo Model of Small Intestine.
Mahe MM, Brown NE, Poling HM, Helmrath MA. Mahe MM, et al. Among authors: poling hm. Methods Mol Biol. 2017;1597:229-245. doi: 10.1007/978-1-4939-6949-4_17. Methods Mol Biol. 2017. PMID: 28361322 Free PMC article.
Erratum to: In Vivo Model of Small Intestine.
Mahe MM, Brown NE, Poling HM, Helmrath MA. Mahe MM, et al. Among authors: poling hm. Methods Mol Biol. 2017;1597:E1. doi: 10.1007/978-1-4939-6949-4_18. Methods Mol Biol. 2017. PMID: 28667364 No abstract available.
Tissue Responses to Shiga Toxin in Human Intestinal Organoids.
Pradhan S, Karve SS, Weiss AA, Hawkins J, Poling HM, Helmrath MA, Wells JM, McCauley HA. Pradhan S, et al. Among authors: poling hm. Cell Mol Gastroenterol Hepatol. 2020;10(1):171-190. doi: 10.1016/j.jcmgh.2020.02.006. Epub 2020 Mar 5. Cell Mol Gastroenterol Hepatol. 2020. PMID: 32145469 Free PMC article.
Gastrointestinal organoids: a next-generation tool for modeling human development.
Singh A, Poling HM, Spence JR, Wells JM, Helmrath MA. Singh A, et al. Among authors: poling hm. Am J Physiol Gastrointest Liver Physiol. 2020 Sep 1;319(3):G375-G381. doi: 10.1152/ajpgi.00199.2020. Epub 2020 Jul 13. Am J Physiol Gastrointest Liver Physiol. 2020. PMID: 32658619 Free PMC article. Review.
21 results