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Expression and function of IL-1R8 (TIR8/SIGIRR): a regulatory member of the IL-1 receptor family in platelets.
Anselmo A, Riva F, Gentile S, Soldani C, Barbagallo M, Mazzon C, Feruglio F, Polentarutti N, Somma P, Carullo P, Angelini C, Bacci M, Mendolicchio GL, Voza A, Nebuloni M, Mantovani A, Garlanda C. Anselmo A, et al. Among authors: polentarutti n. Cardiovasc Res. 2016 Sep;111(4):373-84. doi: 10.1093/cvr/cvw162. Epub 2016 Jun 13. Cardiovasc Res. 2016. PMID: 27297888 Free article.
Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
Véliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C. Véliz Rodriguez T, et al. Among authors: polentarutti n. Infect Immun. 2012 Jan;80(1):100-9. doi: 10.1128/IAI.05695-11. Epub 2011 Oct 24. Infect Immun. 2012. PMID: 22025515 Free PMC article.
High IL-1R8 expression in breast tumors promotes tumor growth and contributes to impaired antitumor immunity.
Campesato LF, Silva APM, Cordeiro L, Correa BR, Navarro FCP, Zanin RF, Marçola M, Inoue LT, Duarte ML, Molgora M, Pasqualini F, Massara M, Galante P, Barroso-Sousa R, Polentarutti N, Riva F, Costa ET, Mantovani A, Garlanda C, Camargo AA. Campesato LF, et al. Among authors: polentarutti n. Oncotarget. 2017 Jul 25;8(30):49470-49483. doi: 10.18632/oncotarget.17713. Oncotarget. 2017. PMID: 28533483 Free PMC article.
IL1R8 Deficiency Drives Autoimmunity-Associated Lymphoma Development.
Riva F, Ponzoni M, Supino D, Bertilaccio MTS, Polentarutti N, Massara M, Pasqualini F, Carriero R, Innocenzi A, Anselmo A, Veliz-Rodriguez T, Simonetti G, Anders HJ, Caligaris-Cappio F, Mantovani A, Muzio M, Garlanda C. Riva F, et al. Among authors: polentarutti n. Cancer Immunol Res. 2019 Jun;7(6):874-885. doi: 10.1158/2326-6066.CIR-18-0698. Epub 2019 Apr 24. Cancer Immunol Res. 2019. PMID: 31018956 Free PMC article.
The expression pattern of TIR8 is conserved among vertebrates.
Riva F, Polentarutti N, Tribbioli G, Mantovani A, Garlanda C, Turin L. Riva F, et al. Among authors: polentarutti n. Vet Immunol Immunopathol. 2009 Sep 15;131(1-2):44-9. doi: 10.1016/j.vetimm.2009.03.009. Epub 2009 Mar 24. Vet Immunol Immunopathol. 2009. PMID: 19386369
114 results