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Imprinting of Skin/Inflammation Homing in CD4+ T Cells Is Controlled by DNA Methylation within the Fucosyltransferase 7 Gene.
Pink M, Ratsch BA, Mardahl M, Durek P, Polansky JK, Karl M, Baumgrass R, Wallner S, Cadenas C, Gianmoena K, Floess S, Chen W, Nordstroem K, Tierling S, Olek S, Walter J, Hamann A, Syrbe U. Pink M, et al. Among authors: polansky jk. J Immunol. 2016 Oct 15;197(8):3406-3414. doi: 10.4049/jimmunol.1502434. Epub 2016 Sep 2. J Immunol. 2016. PMID: 27591321
Epigenetic control of the foxp3 locus in regulatory T cells.
Floess S, Freyer J, Siewert C, Baron U, Olek S, Polansky J, Schlawe K, Chang HD, Bopp T, Schmitt E, Klein-Hessling S, Serfling E, Hamann A, Huehn J. Floess S, et al. PLoS Biol. 2007 Feb;5(2):e38. doi: 10.1371/journal.pbio.0050038. PLoS Biol. 2007. PMID: 17298177 Free PMC article.
DNA methylation controls Foxp3 gene expression.
Polansky JK, Kretschmer K, Freyer J, Floess S, Garbe A, Baron U, Olek S, Hamann A, von Boehmer H, Huehn J. Polansky JK, et al. Eur J Immunol. 2008 Jun;38(6):1654-63. doi: 10.1002/eji.200838105. Eur J Immunol. 2008. PMID: 18493985 Free article.
Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus.
Toker A, Engelbert D, Garg G, Polansky JK, Floess S, Miyao T, Baron U, Düber S, Geffers R, Giehr P, Schallenberg S, Kretschmer K, Olek S, Walter J, Weiss S, Hori S, Hamann A, Huehn J. Toker A, et al. Among authors: polansky jk. J Immunol. 2013 Apr 1;190(7):3180-8. doi: 10.4049/jimmunol.1203473. Epub 2013 Feb 18. J Immunol. 2013. PMID: 23420886
Epigenomic Profiling of Human CD4+ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development.
Durek P, Nordström K, Gasparoni G, Salhab A, Kressler C, de Almeida M, Bassler K, Ulas T, Schmidt F, Xiong J, Glažar P, Klironomos F, Sinha A, Kinkley S, Yang X, Arrigoni L, Amirabad AD, Ardakani FB, Feuerbach L, Gorka O, Ebert P, Müller F, Li N, Frischbutter S, Schlickeiser S, Cendon C, Fröhler S, Felder B, Gasparoni N, Imbusch CD, Hutter B, Zipprich G, Tauchmann Y, Reinke S, Wassilew G, Hoffmann U, Richter AS, Sieverling L; DEEP Consortium; Chang HD, Syrbe U, Kalus U, Eils J, Brors B, Manke T, Ruland J, Lengauer T, Rajewsky N, Chen W, Dong J, Sawitzki B, Chung HR, Rosenstiel P, Schulz MH, Schultze JL, Radbruch A, Walter J, Hamann A, Polansky JK. Durek P, et al. Among authors: polansky jk. Immunity. 2016 Nov 15;45(5):1148-1161. doi: 10.1016/j.immuni.2016.10.022. Immunity. 2016. PMID: 27851915 Free article.
Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.
Schmidt F, Gasparoni N, Gasparoni G, Gianmoena K, Cadenas C, Polansky JK, Ebert P, Nordström K, Barann M, Sinha A, Fröhler S, Xiong J, Dehghani Amirabad A, Behjati Ardakani F, Hutter B, Zipprich G, Felder B, Eils J, Brors B, Chen W, Hengstler JG, Hamann A, Lengauer T, Rosenstiel P, Walter J, Schulz MH. Schmidt F, et al. Among authors: polansky jk. Nucleic Acids Res. 2017 Jan 9;45(1):54-66. doi: 10.1093/nar/gkw1061. Epub 2016 Nov 29. Nucleic Acids Res. 2017. PMID: 27899623 Free PMC article.
24 results