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Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials.
Clément K, van den Akker E, Argente J, Bahm A, Chung WK, Connors H, De Waele K, Farooqi IS, Gonneau-Lejeune J, Gordon G, Kohlsdorf K, Poitou C, Puder L, Swain J, Stewart M, Yuan G, Wabitsch M, Kühnen P; Setmelanotide POMC and LEPR Phase 3 Trial Investigators. Clément K, et al. Among authors: poitou c. Lancet Diabetes Endocrinol. 2020 Dec;8(12):960-970. doi: 10.1016/S2213-8587(20)30364-8. Epub 2020 Oct 30. Lancet Diabetes Endocrinol. 2020. PMID: 33137293 Clinical Trial.
Leptin therapy for partial lipodystrophy linked to a PPAR-gamma mutation.
Guettier JM, Park JY, Cochran EK, Poitou C, Basdevant A, Meier M, Clément K, Magré J, Gorden P. Guettier JM, et al. Among authors: poitou c. Clin Endocrinol (Oxf). 2008 Apr;68(4):547-554. doi: 10.1111/j.1365-2265.2007.03095.x. Epub 2007 Dec 10. Clin Endocrinol (Oxf). 2008. PMID: 18076675 Free PMC article.
GLUT2 accumulation in enterocyte apical and intracellular membranes: a study in morbidly obese human subjects and ob/ob and high fat-fed mice.
Ait-Omar A, Monteiro-Sepulveda M, Poitou C, Le Gall M, Cotillard A, Gilet J, Garbin K, Houllier A, Château D, Lacombe A, Veyrie N, Hugol D, Tordjman J, Magnan C, Serradas P, Clément K, Leturque A, Brot-Laroche E. Ait-Omar A, et al. Among authors: poitou c. Diabetes. 2011 Oct;60(10):2598-607. doi: 10.2337/db10-1740. Epub 2011 Aug 18. Diabetes. 2011. PMID: 21852673 Free PMC article.
200 results